Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2420908 | 0.88 | TSHR (0.44) | ESR1TSHRCYP3A4TDP1CA1 | |
| SCHEMBL2570936 | 0.86 | ESR1 (0.46) | ESR1ESR2TSHRCYP3A4CA1 | |
| SCHEMBL15051456 | 0.80 | ESR1 (0.42) | ESR1ESR2TSHRCYP3A4TDP1 | |
| SCHEMBL1596933 | 0.79 | ALOX15 (0.39) | ESR1ESR2TSHRCYP3A4TDP1 | |
| SCHEMBL30343449 | 0.79 | ALOX15 (0.39) | ESR1ESR2TSHRCYP3A4TDP1 | |
| SCHEMBL8376286 | 0.79 | HSD17B10 (0.42) | ESR1ESR2TSHRCYP3A4TDP1 | |
| SCHEMBL7257754 | 0.78 | CYP2C9 (0.53) | ESR1ESR2TSHRCYP3A4CA1 | |
| SCHEMBL4603027 | 0.78 | GABRA1 (0.47) | TSHRCYP3A4CA1CA2CYP2C19 | |
| SCHEMBL15998074 | 0.78 | PTGS1 (0.43) | TSHRCYP3A4TDP1CA1CA2 | |
| SCHEMBL9532953 | 0.77 | HMGB1 (0.50) | ESR1ESR2TSHRCYP3A4CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763560-A1 | POLYARYLATE COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 2007-03-21 | — | — | EP | claimed |
| WO-2006012161-A1 | POLYARYLATE COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 2006-02-02 | — | — | WO | claimed |
| WO-2008051849-A1 | TERT-BUTYLHYDROQUINONE POLYCARBONATES | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-05-02 | — | — | WO | disclosed |