SCHEMBL4603385

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4633571	0.91	CXCR2 (0.55)	CXCR2LMNAMAPTLTA4HSENP5
	SCHEMBL4603395	0.90	FFAR1 (0.53)	CXCR2MAOBLMNAL3MBTL1FFAR1
	SCHEMBL4635068	0.85	LMNA (0.51)	CXCR2LMNAMAPTL3MBTL1ALDH1A1
	SCHEMBL4618003	0.82	CXCR2 (0.56)	CXCR2MAOBLMNAMAPTL3MBTL1
	SCHEMBL4602975	0.81	CXCR2 (0.55)	CXCR2MAOBLMNAMAPTL3MBTL1
	SCHEMBL4604453	0.80	CXCR2 (0.59)	CXCR2MAOBLMNAMAPTL3MBTL1
	SCHEMBL4603993	0.80	SENP5 (0.47)	CXCR2MAOBLMNASENP5SENP2
	SCHEMBL4604985	0.80	CXCR2 (0.54)	CXCR2LMNAMAPTL3MBTL1PPARG
	SCHEMBL4635016	0.80	CXCR2 (0.43)	CXCR2LMNAMAPTL3MBTL1LTA4H
	SCHEMBL4603643	0.79	ALDH1A1 (0.46)	CXCR2MAOBLMNAMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.