SCHEMBL460419

SCHEMBL460419

Cc1cc(C)cc(P(Cl)c2cc(C)cc(C)c2)c1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
TSHR P16473 3/20 0.42
ACHE P22303 2/20 0.35
TPMT P51580 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32
C1S P09871 1/20 0.32
PRSS3 P35030 1/20 0.32
SELL P14151 1/20 0.32
SELP P16109 1/20 0.32
SELE P16581 1/20 0.32
RAPGEF4 Q8WZA2 2/20 0.31
CYP3A4 P08684 1/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28382970 0.84 ACHE (0.39) ALDH1A1TSHRACHETPMTSMN1; SMN2
SCHEMBL28452721 0.80 ALDH1A1 (0.42) ALDH1A1TSHRACHETPMTPRSS1
SCHEMBL2885211 0.80 ALDH1A1 (0.42) ALDH1A1TSHRACHETPMTPRSS1
SCHEMBL8033135 0.75
SCHEMBL16351489 0.74 RAPGEF4 (0.43) RAPGEF4
SCHEMBL26115 0.73
SCHEMBL341533 0.73 ALDH1A1 (0.67) ALDH1A1TSHRACHETPMTSMN1; SMN2
SCHEMBL503226 0.72 ALDH1A1 (0.47) ALDH1A1TSHRACHETPMTSMN1; SMN2
SCHEMBL25219985 0.71 ALDH1A1 (0.35) ALDH1A1TSHRACHEPRSS1PRSS2
SCHEMBL667708 0.71 ACHE (0.50) ALDH1A1TSHRACHESMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1598053-B1 Use of a composition containing at least one phosphine as majority reducing agent to remove the artificial colour of keratinic fibres OREAL (FR) 2006-12-20 EP claimed
EP-1598053-A1 Use of a composition containing at least one phosphine as majority reducing agent to remove the artificial colour of keratinic fibres L'OREAL (FR) 2005-11-23 EP claimed
US-20050251928-A1 Method for stripping artificial color from keratin fibers L'OREAL (FR) 2005-11-17 US claimed
EP-4509515-B1 LIGAND COMPOUND, ORGANIC CHROMIUM COMPOUND, AND CATALYST COMPOSITION COMPRISING SAME LG CHEMICAL LTD (KR) 2026-04-29 EP disclosed
EP-4215537-B1 LIGAND COMPOUND, ORGANOCHROMIUM COMPOUND, AND CATALYST SYSTEM COMPRISING THE SAME LG CHEMICAL LTD (KR) 2026-04-29 EP disclosed
EP-4700031-A1 LIGAND COMPOUND, ORGANIC CHROMIUM COMPOUND, AND CATALYST COMPOSITION COMPRISING SAME LG Chem, Ltd. (KR) 2026-02-25 EP disclosed
EP-4700033-A1 LIGAND COMPOUND, ORGANIC CHROMIUM COMPOUND AND CATALYST COMPOSITION COMPRISING SAME LG Chem, Ltd. (KR) 2026-02-25 EP disclosed
US-20250381558-A1 Ligand Compound, Organic Chromium Compound, and Catalyst Compositions Containing the Same LG CHEM, LTD. (KR) 2025-12-18 US disclosed
US-20250368598-A1 CATALYTIC CARBOXYCARBONYLATION OF ALKENES TO FORM ANHYDRIDES BHATTACHARYA SHRABANTI (US) 2025-12-04 US disclosed
EP-4559921-B1 LIGAND COMPOUND, ORGANIC CHROMIUM COMPOUND AND CATALYST COMPOSITION COMPRISING SAME LG CHEMICAL LTD (KR) 2025-11-26 EP disclosed
US-20250333427-A1 Ligand Compound, Organic Chromium Compound, and Catalyst Composition Including the Same LG CHEM, LTD. (KR) 2025-10-30 US disclosed
EP-1254885-A1 PROCESS FOR PREPARING OPTICALLY ACTIVE SECONDARY ALCOHOLS HAVING NITROGENOUS OR OXYGENIC FUNCTIONAL GROUPS Asahi Kasei Kabushiki Kaisha (JP) 2002-11-06 EP disclosed
WO-2002014330-A1 CYCLOALIPHATIC/AROMATIC DIPHOSPHINES AND USE THEREOF IN CATALYSIS DEGUSSA AG (DE) 2002-02-21 WO disclosed
US-6348612-B1 FORM COMPLEXES USED AS CATALYSTS FOR ENANTIOSELECTIVE REACTIONS SUCH AS ASYMMETRIC HYDROGENATIONS, ENANTIOSELECTIVE HYDROGEN DISPLACEMENTS, ALLYLIC SUBSTITUTION REACTIONS ROCHE VITAMINS INC. 2002-02-19 US disclosed
US-6084133-A REACTING A PHOSPHINE HALIDE WITH A METAL, THEN PROTONATION RESULTING DIORGANO-SUBSTITUTED METAL PHOSPHIDE; SIMPLIFICATION, NONTOXIC, EFFICIENCY KANKYO KAGAKU CENTER CO., LTD. (JP) 2000-07-04 US disclosed
EP-0739333-B1 SELECTIVE ASYMMETRIC HYDROGENATION OF DEHYDROAMINO ACID DERIVATIVES USING RHODIUM AND IRIDIUM DIPHOSPHINITE CARBOHYDRATE CATALYST COMPOSITIONS DU PONT (US) 1998-10-14 EP disclosed
EP-0864576-A1 Novel amidophospine-phosphinite derivatives F. HOFFMANN-LA ROCHE AG (CH) 1998-09-16 EP disclosed
US-5510507-A COORDINATION CATALYSTS; EFFICIENT ENANTIOSELECTIVITY E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-04-23 US disclosed
US-5481006-A PREPARATION OF INTERMEDIATES FOR PHARMACEUTICALS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-01-02 US disclosed
US-5223632-A 2,2'-BIS(DI-(3,5-DIALKYLPHENYL)PHOSPHINO)-1,1'-BINAPHTHYL AND TRANSITION METAL COMPLEX CONTAINING THE SAMD LIGAND TAKASAGO INTERNATIONAL CORPORATION (JP) 1993-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250368598-A1 CATALYTIC CARBOXYCARBONYLATION OF ALKENES TO FORM ANHYDRIDES CA4, CA12, CA14 ALDH1A1 688/4885TSHR 4615/4885ACHE 2398/4885
US-20250333427-A1 Ligand Compound, Organic Chromium Compound, and Catalyst Composition Including the Same OXER1, ORC3, CRKL ALDH1A1 3554/4885TSHR 1944/4885ACHE 70/4885
US-20250381558-A1 Ligand Compound, Organic Chromium Compound, and Catalyst Compositions Containing the Same EXOC1, OXER1, ORC3 ALDH1A1 3116/4885TSHR 2040/4885ACHE 81/4885
US-20050251928-A1 Method for stripping artificial color from keratin fibers KRT18, DSG1, JUP ALDH1A1 4512/4885TSHR 4245/4885ACHE 704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.