Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602671 | 1.00 | SPHK1 (0.47) | SPHK1DNM1THRBTSHRLPAR1 | |
| SCHEMBL28798377 | 1.00 | SPHK1 (0.47) | SPHK1DNM1THRBTSHRLPAR1 | |
| SCHEMBL9807770 | 1.00 | SPHK1 (0.47) | SPHK1DNM1THRBTSHRLPAR1 | |
| Hydrochloric Acid SCHEMBL7902390 | 0.98 | DNM1 (0.50) | SPHK1DNM1THRBTSHRLPAR1 | |
| SCHEMBL27564512 | 0.98 | SPHK1 (0.44) | SPHK1DNM1THRBLPAR1LPAR3 | |
| Hydrochloric Acid SCHEMBL14892988 | 0.95 | DNM1 (0.47) | SPHK1DNM1LPAR1LPAR3LPAR2 | |
| SCHEMBL6667445 | 0.91 | SPHK1 (0.37) | SPHK1DNM1TSHR | |
| SCHEMBL9807866 | 0.88 | SPHK1 (0.50) | SPHK1DNM1THRBTSHRLPAR1 | |
| Propionic Acid SCHEMBL20264379 | 0.87 | NAAA (0.43) | SPHK1TSHRMEN1KMT2A | |
| SCHEMBL10726362 | 0.86 | DNM1 (0.47) | SPHK1DNM1THRBTSHRLPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080227865-A1 | COLIPSE-LIPASE INHIBITORS IN THE PREPARATION OF A PHARMACEUTICAL COMPOSITION IN ORDER TO PREVENT OBESITY | FORSKARPATENT I SYD AB (SE) | 2008-09-18 | — | — | US | disclosed |
| US-7425577-B2 | Lipase-colipase inhibitor | FORSKARPATENT 1 SYD AB (SE) | 2008-09-16 | — | — | US | disclosed |
| EP-1660062-B1 | USE OF COLIPASE-LIPASE INHIBITORS IN THE PREPARATION OF A PHARMACEUTICAL COMPOSITION IN ORDER TO PREVENT OBESITY | FORSKARPATENT I SYD AB (SE) | 2008-07-09 | — | — | EP | disclosed |
| US-20060199869-A1 | Lipase-colipase inhibitor | FORSKARPATENT 1 SYD AB (SE) | 2006-09-07 | — | — | US | disclosed |
| EP-1660062-A1 | USE OF COLIPASE-LIPASE INHIBITORS IN THE PREPARATION OF A PHARMACEUTICAL COMPOSITION IN ORDER TO PREVENT OBESITY | Forskarpatent i Syd AB (SE) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005018625-A1 | USE OF COLIPASE-LIPASE INHIBITORS IN THE PREPARATION OF A PHARMACEUTICAL COMPOSITION IN ORDER TO PREVENT OBESITY | FORSKARPATENT I SYD AB (SE) | 2005-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199869-A1 | Lipase-colipase inhibitor | PNLIP, LPL, LIPC | SPHK1 2049/4885DNM1 3975/4885THRB 2820/4885 |
| US-20080227865-A1 | COLIPSE-LIPASE INHIBITORS IN THE PREPARATION OF A PHARMACEUTICAL COMPOSITION IN ORDER TO PREVENT OBESITY | PNLIP, LIPE, LPL | SPHK1 2601/4885DNM1 4358/4885THRB 2875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.