SCHEMBL4604496

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4604182	0.92	SENP5 (0.51)	SENP5SENP2SENP1SMN1; SMN2NPC1
	SCHEMBL4604118	0.92	SENP5 (0.52)	SENP5SENP2SENP1SMN1; SMN2NPC1
	SCHEMBL4603662	0.83	ALDH1A1 (0.51)	SENP5SENP2SENP1SMN1; SMN2RAB9A
	SCHEMBL4602743	0.83	ALOX5 (0.46)	SENP5SENP2SENP1NPC1RAB9A
	SCHEMBL4603197	0.82	SENP5 (0.48)	SENP5SENP2SENP1MAPT
	SCHEMBL4603975	0.82	MEN1 (0.54)	SENP5SENP2SENP1SMN1; SMN2NPC1
	SCHEMBL4604741	0.82	MAOB (0.60)	SENP5SENP2SENP1SMN1; SMN2NPC1
	SCHEMBL4604734	0.81	SENP5 (0.50)	SENP5SENP2SENP1MRGPRX4MAPT
	SCHEMBL4604537	0.80	SENP2 (0.60)	SENP5SENP2SENP1KDM4E
	SCHEMBL4603300	0.80	PTPN2 (0.51)	SENP5SENP2SENP1NPC1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.