Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | USP8 | P40818 | 1/20 | 0.32 |
| ▸ | USP5 | P45974 | 1/20 | 0.32 |
| ▸ | USP4 | Q13107 | 1/20 | 0.32 |
| ▸ | USP7 | Q93009 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16707459 | 0.87 | ALDH1A1 (0.43) | MAPTALDH1A1LMNAHPGDCA2 | |
| SCHEMBL16707435 | 0.78 | ALDH1A1 (0.38) | MAPTALDH1A1MEN1LMNAHPGD | |
| SCHEMBL29599714 | 0.75 | ALOX15 (0.50) | ARMAPTALDH1A1ALOX15HSD17B10 | |
| SCHEMBL5150171 | 0.75 | ALOX15 (0.50) | ARMAPTALDH1A1ALOX15HSD17B10 | |
| SCHEMBL5570280 | 0.75 | GAA (0.39) | ARMAPTALDH1A1ALOX15HSD17B10 | |
| SCHEMBL3409348 | 0.73 | LMNA (0.61) | ARMAPTALDH1A1ALOX15HSD17B10 | |
| SCHEMBL21495996 | 0.73 | ALDH1A1 (0.40) | ARMAPTALDH1A1CA2CA5A | |
| SCHEMBL1507626 | 0.73 | ALOX15 (0.43) | ARMAPTALDH1A1ALOX15HSD17B10 | |
| SCHEMBL29457565 | 0.71 | TRPA1 (0.53) | ARMAPTALDH1A1ALOX15HSD17B10 | |
| SCHEMBL68013 | 0.71 | TRPA1 (0.53) | ARMAPTALDH1A1ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945620-A2 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007056366-A2 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2007-05-18 | — | — | WO | disclosed |