SCHEMBL4607199

SCHEMBL4607199

O=c1nc2c(-c3ccccc3)c(-c3ccccc3)nc-2c1=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
MAPT P10636 2/20 0.46
HTT P42858 1/20 0.46
XDH P47989 1/20 0.46
ADK P55263 2/20 0.42
ADORA2A P29274 1/20 0.41
ADORA1 P30542 1/20 0.41
KDM4E B2RXH2 5/20 0.39
ALDH1A1 P00352 3/20 0.39
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
HPGD P15428 2/20 0.36
TSHR P16473 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TP53 P04637 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL643990 0.81 ADORA2A (0.42) LMNAMAPTHTTADORA2AADORA1
SCHEMBL38657449 0.80 RXRA (0.40) LMNAMAPTHTTADORA2AADORA1
SCHEMBL5366222 0.74 XDH (0.48) LMNAMAPTHTTXDHADK
SCHEMBL13203111 0.72 XDH (0.47) LMNAMAPTHTTXDHADK
SCHEMBL12787092 0.72 XDH (0.47) LMNAMAPTHTTXDHADK
SCHEMBL12306162 0.70 ADK (0.60) LMNAMAPTHTTXDHADK
SCHEMBL771038 0.70 KDM4E (0.46) LMNAMAPTHTTXDHADK
SCHEMBL13203113 0.70 XDH (0.46) LMNAMAPTHTTXDHADK
SCHEMBL10205902 0.69 L3MBTL1 (0.54) LMNAMAPTXDHADKKDM4E
SCHEMBL10205859 0.69 KDM4E (0.50) LMNAMAPTXDHADKADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116969953-A Diphenyl pyrrolo-pyrrole-dione derivative, pigment composition and application thereof 山东凯瑞尔光电科技有限公司 2023-10-31 CN claimed
CN-116969952-A Diphenyl pyrrolo-pyrrole-dione derivative and pigment composition thereof 山东凯瑞尔光电科技有限公司 2023-10-31 CN claimed
CN-111607235-A Ingredient of color asphalt and preparation method thereof 西北民族大学 2020-09-01 CN claimed
CN-118812566-A Hyperbranched triazine modified pyrrolopyrrolidone compound as well as preparation method and application thereof 山东凯瑞尔光电科技有限公司 2024-10-22 CN disclosed
CN-118812565-A Triazine derivative modified halogenated diphenyl pyrrolopyrrole dione compound and preparation method and application thereof 山东凯瑞尔光电科技有限公司 2024-10-22 CN disclosed
CN-118812565-A Triazine derivative modified halogenated diphenyl pyrrolopyrrole dione compound and preparation method and application thereof 山东凯瑞尔光电科技有限公司 2024-10-22 CN disclosed
CN-118812566-A Hyperbranched triazine modified pyrrolopyrrolidone compound as well as preparation method and application thereof 山东凯瑞尔光电科技有限公司 2024-10-22 CN disclosed
CN-118530241-A Thioether substituted diphenyl pyrrolopyrrole diketone and preparation method and application thereof 山东凯瑞尔光电科技有限公司 2024-08-23 CN disclosed
CN-116969953-A Diphenyl pyrrolo-pyrrole-dione derivative, pigment composition and application thereof 山东凯瑞尔光电科技有限公司 2023-10-31 CN disclosed
CN-116969952-A Diphenyl pyrrolo-pyrrole-dione derivative and pigment composition thereof 山东凯瑞尔光电科技有限公司 2023-10-31 CN disclosed
CN-116969953-A Diphenyl pyrrolo-pyrrole-dione derivative, pigment composition and application thereof 山东凯瑞尔光电科技有限公司 2023-10-31 CN disclosed
WO-2002076988-A2 TERT. ALKYLPHENOXY SUBSTITUTED POLYCYCLIC COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2002-10-03 WO disclosed
US-6413655-B2 GUEST CHROMOPHORE EMBEDDED IN MATRIX OF HOST CHROMOPHORE, OR HOST CHROMOPHORE AND AN EFFECTIVE AMOUNT OF A GUEST CHROMOPHORE BOTH EMBEDDED IN POLYMER MATRIX; ELECTROLUMINESCENCE CIBA SPECIALTY CHEMICALS CORPORATION 2002-07-02 US disclosed
US-20010016269-A1 FLUORESCENT MATERIALS AND THEIR USE CIBA SPECIALTY CHEMICALS CORP. 2001-08-23 US disclosed
US-6066202-A IMPROVED GLOSS, RHEOLOGY AND STORAGE STABILITY CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-05-23 US disclosed
EP-0968254-A1 FLUORESCENT MATERIALS AND THEIR USE Ciba SC Holding AG (CH) 2000-01-05 EP disclosed
WO-1998033862-A1 FLUORESCENT MATERIALS AND THEIR USE CIBA SPECIALITY CHEMICALS HOLDING INC. (CH) 1998-08-06 WO disclosed
EP-0524904-B1 Process for conditioning organic pigments CIBA GEIGY AG (CH) 1996-09-04 EP disclosed
US-5194088-A PROCESS FOR CONDITIONING ORGANIC PIGMENTS CIBA-GEIGY CORPORATION (US) 1993-03-16 US disclosed
EP-0524904-A2 Process for conditioning organic pigments CIBA-GEIGY AG (CH) 1993-01-27 EP disclosed