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SCHEMBL4607858

SCHEMBL4607858

COC1(OC)[C@H](OC(CC(=O)O)C(=O)O)[C@@H](CO)O[C@]1(n1cc(C)c(=O)[nH]c1=O)C(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ RNASE1 P07998 1/20 0.35
▸ TK1 P04183 8/20 0.34
▸ TYMP P19971 1/20 0.33
▸ TK2 O00142 7/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1706308 0.83 RNASE1 (0.39) RNASE1TK1TK2
SCHEMBL6756344 0.80 RNASE1 (0.37) RNASE1TK1TK2
SCHEMBL5133064 0.76 KDM4E (0.41) TYMP
SCHEMBL30694951 0.76 TK1 (0.34) RNASE1TK1TK2
SCHEMBL1705788 0.75 ABCG2 (0.34) TK1TK2
SCHEMBL7640426 0.75 RNASE1 (0.39) RNASE1TK1TK2
SCHEMBL7908351 0.75 TK2 (0.35) RNASE1TK1TK2
SCHEMBL1705943 0.74 TK1 (0.35) TK1TK2
SCHEMBL29414069 0.74 LMNA (0.37) RNASE1
SCHEMBL3612842 0.74 PYGM (0.38) RNASE1TK1TYMPTK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1945750-A2 MICROARRAY HAVING A BASE CLEAVABLE SUCINATE LINKER Combimatrix Corporation (US) 2008-07-23 — — EP claimed
WO-2007035500-A2 MICROARRAY HAVING A BASE CLEAVABLE SUCCINATE LINKER COMBIMATRIX CORPORATION (US) 2007-03-29 — — WO claimed