Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 11/20 | 0.35 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.35 |
| ▸ | TK1 | P04183 | 6/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5954363 | 0.95 | TK2 (0.33) | TK2RNASE1TK1 | |
| SCHEMBL1706308 | 0.91 | RNASE1 (0.39) | TK2RNASE1TK1 | |
| SCHEMBL6756344 | 0.85 | RNASE1 (0.37) | TK2RNASE1TK1 | |
| SCHEMBL29414069 | 0.80 | LMNA (0.37) | RNASE1 | |
| SCHEMBL3612842 | 0.80 | PYGM (0.38) | TK2RNASE1TK1 | |
| SCHEMBL5031652 | 0.80 | — | — | |
| SCHEMBL9499952 | 0.79 | — | — | |
| SCHEMBL1705943 | 0.79 | TK1 (0.35) | TK2TK1 | |
| SCHEMBL7640426 | 0.78 | RNASE1 (0.39) | TK2RNASE1TK1 | |
| SCHEMBL29414053 | 0.78 | RNASE1 (0.30) | RNASE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197949-B1 | SUPPORTS AND NOVEL PROCESSES FOR BINDING OLIGONUCLEOTIDES | CIS BIO INTERNATIONAL (FR) | 2001-03-06 | — | — | US | disclosed |
| US-5864031-A | REACTING POLYMER SUPPORTED NUCLEOSIDE (2',5'-DIDEOXY-5'-S(4,4-DIMETHOXYTRITYL) WITH AN ACID IN PRESENCE OF ARYLSULFENYL CHLORIDE, REACTING ASYMMETRICAL DISULFIDE OF NUCLEOSIDE WITH 3'-H-PHOSPHONATE SYNTHON | AMGEN INC. (US) | 1999-01-26 | — | — | US | disclosed |
| US-5837859-A | COPOLYMER AND NUCLEOTIDES OR HYBRIDS | CIS BIO INTERNATIONAL (FR) | 1998-11-17 | — | — | US | disclosed |
| EP-0691978-B1 | ELECTRONICALLY CONDUCTIVE POLYMER/NUCLEOTIDE COPOLYMER, PREPARATION METHOD THEREFOR AND USE THEREOF | CIS BIO INT (FR) | 1997-10-08 | — | — | EP | disclosed |
| EP-0772622-A1 | 5'-DITHIO-MODIFIED OLIGONUCLEOTIDES | AMGEN INC. (US) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996004295-A1 | 5'-DITHIO-MODIFIED OLIGONUCLEOTIDES | AMGEN INC. (US) | 1996-02-15 | — | — | WO | disclosed |
| EP-0691978-A1 | ELECTRONICALLY CONDUCTIVE POLYMER/NUCLEOTIDE COPOLYMER, PREPARATION METHOD THEREFOR AND USE THEREOF | CIS BIO INT (FR) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994022889-A1 | ELECTRONICALLY CONDUCTIVE POLYMER/NUCLEOTIDE COPOLYMER, PREPARATION METHOD THEREFOR AND USE THEREOF | CIS BIO INTERNATIONAL (FR) | 1994-10-13 | — | — | WO | disclosed |