Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12071745 | 0.92 | EZH2 (0.32) | ALDH1A1 | |
| SCHEMBL46100 | 0.92 | EPHX2 (0.34) | SIGMAR1ALDH1A1 | |
| SCHEMBL46375 | 0.87 | NPSR1 (0.31) | NPSR1ALDH1A1 | |
| SCHEMBL46059 | 0.86 | SIGMAR1 (0.32) | SIGMAR1 | |
| SCHEMBL15032129 | 0.85 | L3MBTL1 (0.34) | SIGMAR1 | |
| SCHEMBL46114 | 0.83 | MEN1 (0.33) | ALDH1A1 | |
| SCHEMBL12071750 | 0.83 | KDM4E (0.32) | ALDH1A1 | |
| SCHEMBL46054 | 0.81 | L3MBTL1 (0.30) | — | |
| SCHEMBL46140 | 0.81 | TSHR (0.32) | LMNASIGMAR1ALDH1A1 | |
| SCHEMBL46109 | 0.81 | SIGMAR1 (0.33) | NPSR1SIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151249-A2 | METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| WO-2010066780-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-06-17 | — | — | WO | disclosed |