Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.44 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4608914 | 0.88 | SLC6A3 (0.47) | MBTD1L3MBTL3L3MBTL1HRH3 | |
| SCHEMBL4607915 | 0.88 | ACHE (0.45) | ALDH1A1MBTD1L3MBTL3L3MBTL1BCHE | |
| SCHEMBL4608505 | 0.84 | HRH3 (0.53) | KDM4EMBTD1L3MBTL3L3MBTL1HRH3 | |
| SCHEMBL4608156 | 0.83 | SLC6A3 (0.46) | MBTD1L3MBTL3L3MBTL1HRH3 | |
| SCHEMBL4608628 | 0.82 | HRH3 (0.42) | MBTD1L3MBTL3L3MBTL1HRH3 | |
| SCHEMBL4609186 | 0.81 | HRH3 (0.52) | OPRL1MBTD1L3MBTL3L3MBTL1OPRM1 | |
| SCHEMBL4610133 | 0.81 | HRH3 (0.44) | MBTD1L3MBTL3L3MBTL1HRH3 | |
| SCHEMBL4654451 | 0.80 | L3MBTL3 (0.38) | MBTD1L3MBTL3L3MBTL1HRH3 | |
| SCHEMBL4607800 | 0.80 | HRH3 (0.39) | MBTD1L3MBTL3L3MBTL1HRH3 | |
| SCHEMBL14538837 | 0.77 | L3MBTL3 (0.47) | MBTD1L3MBTL3L3MBTL1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948605-A2 | MODULATORS OF THE H3 RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2008-07-30 | — | — | EP | claimed |
| WO-2007061741-A2 | MODULATORS OF THE H3 RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2007-05-31 | — | — | WO | claimed |
| WO-2007061741-A2 | MODULATORS OF THE H3 RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2007-05-31 | — | — | WO | disclosed |