Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12071754 | 0.92 | SIGMAR1 (0.33) | SIGMAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL46128 | 0.90 | L3MBTL1 (0.34) | L3MBTL1 | |
| SCHEMBL46051 | 0.86 | ERBB2 (0.30) | L3MBTL1 | |
| SCHEMBL46131 | 0.84 | SIGMAR1 (0.34) | SIGMAR1ALDH1A1GAA | |
| SCHEMBL46375 | 0.84 | NPSR1 (0.31) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL37755 | 0.84 | L3MBTL1 (0.36) | SIGMAR1L3MBTL1 | |
| SCHEMBL46100 | 0.82 | EPHX2 (0.34) | SIGMAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL46336 | 0.82 | MAPT (0.35) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL46058 | 0.82 | KDM4E (0.34) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL46350 | 0.81 | TSHR (0.31) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151249-A2 | METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| WO-2010066780-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-06-17 | — | — | WO | disclosed |