Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 2/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11124464 | 0.95 | MAPT (0.47) | NPC1JAK2RAB9APAX8MEN1 | |
| SCHEMBL5880844 | 0.87 | ALDH1A1 (0.46) | RAB9AMEN1KMT2ALMNAHTT | |
| SCHEMBL28153546 | 0.82 | ADRA2C (0.42) | MEN1KMT2ALMNAHTTCRHBP | |
| SCHEMBL2522995 | 0.80 | KCNA3 (0.39) | MEN1KMT2ALMNACRHBPCRHR2 | |
| SCHEMBL162872 | 0.79 | ALDH1A1 (0.48) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL3478215 | 0.79 | NPC1 (0.42) | NPC1JAK2RAB9APAX8MEN1 | |
| SCHEMBL11229651 | 0.77 | L3MBTL1 (0.44) | NPC1RAB9AALDH1A1ATML3MBTL1 | |
| SCHEMBL3107378 | 0.76 | KCNH2 (0.56) | KCNH2 | |
| SCHEMBL9057912 | 0.76 | TP53 (0.39) | NPC1JAK2RAB9APAX8MEN1 | |
| SCHEMBL147785 | 0.76 | ALDH1A1 (0.43) | MEN1KMT2ALMNAMAPTCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080099112-A1 | Reduced sensitivity melt-pourable Tritonal replacements | ALLIANT TECHSYSTEMS INC. | 2008-05-01 | — | — | US | claimed |
| US-7067024-B2 | Reduced sensitivity, melt-pourable TNT replacements | ALLIANT TECHSYSTEMS INC. (US) | 2006-06-27 | — | — | US | claimed |
| US-6964714-B2 | Reduced sensitivity, melt-pourable tritonal replacements | ALLIANT TECHSYSTEMS INC. (US) | 2005-11-15 | — | — | US | claimed |
| EP-1399399-A1 | REDUCED SENSITIVITY, MELT-POURABLE TRITONAL REPLACEMENTS | ALLIANT TECHSYSTEMS INC. (US) | 2004-03-24 | — | — | EP | claimed |
| EP-1399400-A1 | REDUCED SENSITIVITY, MELT-POURABLE TNT REPLACEMENTS | ALLIANT TECHSYSTEMS INC. (US) | 2004-03-24 | — | — | EP | claimed |
| US-20030140993-A1 | Reduced sensitivity, melt-pourable tritonal replacements | NORTHROP GRUMMAN SYSTEMS CORPORATION | 2003-07-31 | — | — | US | claimed |
| WO-2003002486-A1 | REDUCED SENSITIVITY, MELT-POURABLE TNT REPLACEMENTS | ALLIANT TECHSYSTEMS INC. (US) | 2003-01-09 | — | — | WO | claimed |
| WO-2003002485-A1 | REDUCED SENSITIVITY, MELT-POURABLE TRITONAL REPLACEMENTS | ALLIANT TECHSYSTEMS INC. (US) | 2003-01-09 | — | — | WO | claimed |
| US-20030005988-A1 | Reduced sensitivity, melt-pourable TNT replacements | NORTHROP GRUMMAN SYSTEMS CORPORATION | 2003-01-09 | — | — | US | claimed |
| US-11879019-B2 | Dual-enzyme responsive peptides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-01-23 | — | — | US | disclosed |
| US-20200199177-A1 | Dual-Enzyme Responsive Peptides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-06-25 | — | — | US | disclosed |
| EP-3555280-A1 | DUAL-ENZYME RESPONSIVE PEPTIDES | The Regents of The University of California (US) | 2019-10-23 | — | — | EP | disclosed |
| WO-2018118902-A1 | DUAL-ENZYME RESPONSIVE PEPTIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-06-28 | — | — | WO | disclosed |
| EP-1982749-A2 | Novel hair colouring compositions for use in oxidative hair dyeing | The Procter and Gamble Company (US) | 2008-10-22 | — | — | EP | disclosed |
| WO-2001046091-A1 | REDUCED SENSITIVITY MELT-CAST EXPLOSIVES | DOLL, DANIEL, W. | 2001-06-28 | — | — | WO | disclosed |
| WO-2001014343-A1 | SUBSTITUTED BENZIMIDAZOLES AS NON-NUCLEOSIDE INHIBITORS OF REVERSE TRANSCRIPTASE | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2001-03-01 | — | — | WO | disclosed |
| EP-0963371-A1 | SUBSTITUTED BENZIMIDAZOLES AS NON-NUCLEOSIDE INHIBITORS OF REVERSE TRANSCRIPTASE | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1999-12-15 | — | — | EP | disclosed |
| WO-1998037072-A1 | SUBSTITUTED BENZIMIDAZOLES AS NON-NUCLEOSIDE INHIBITORS OF REVERSE TRANSCRIPTASE | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1998-08-27 | — | — | WO | disclosed |
| EP-0292911-A2 | Process for the preparation of pure nitro-aminobenzene-compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-30 | — | — | EP | disclosed |
| US-4600797-A | NITRATING AN AMINOBENZENE WHICH HAS A PROTECTEDD AMINO GROUP | BAYER AKTIENGESELLSCHAFT (DE) | 1986-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11879019-B2 | Dual-enzyme responsive peptides | DNPEP, PEPD, APEH | NPC1 4867/4885JAK2 3820/4885RAB9A 2836/4885 |
| US-20200199177-A1 | Dual-Enzyme Responsive Peptides | DNPEP, PEPD, APEH | NPC1 4867/4885JAK2 3820/4885RAB9A 2836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.