SCHEMBL4612809

SCHEMBL4612809

CCCC(SC(C)=O)[SiH](OCC)OCC

nearest known ligand 0.30

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.30
AKR1A1 P14550 1/20 0.30
CHRM3 P20309 1/20 0.30
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
ADRA1A P35348 1/20 0.30
HRH1 P35367 1/20 0.30
DRD3 P35462 1/20 0.30
SLC6A3 Q01959 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC2 Q92769 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2557501 0.76
SCHEMBL4354368 0.76
SCHEMBL11783468 0.72
SCHEMBL550781 0.72
SCHEMBL21630199 0.72
SCHEMBL11734520 0.69
SCHEMBL3341050 0.68 TSHR (0.33) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL6056824 0.67
SCHEMBL504646 0.64 OPRM1 (0.39)
SCHEMBL7587948 0.64 ALDH1A1 (0.41) CHRM1AKR1A1CHRM3HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0991698-B1 SILICONE OLIGOMERS AND CURABLE COMPOSITIONS CONTAINING SAME MOMENTIVE PERFORMANCE MAT INC (US) 2012-10-24 EP disclosed
EP-1194219-B1 HYDROLYZABLE SILANE EMULSIONS AND METHOD FOR PREPARING THE SAME MOMENTIVE PERFORMANCE MAT INC (US) 2008-03-12 EP disclosed
US-6515043-B2 Surface treatment of filler CROMPTON CORPORATION 2003-02-04 US disclosed
US-6395856-B1 CURABLE POLYSILOXANES FOR PROTECTIVE COATINGS FOR WIRES CROMPTON CORPORATION 2002-05-28 US disclosed
EP-1194219-A1 HYDROLYZABLE SILANE EMULSIONS AND METHOD FOR PREPARING THE SAME Crompton Corporation (US) 2002-04-10 EP disclosed
US-20010021761-A1 Silicone oligomers with heigher alkoxy groups MOMENTIVE PERFORMANCE MATERIALS INC. 2001-09-13 US disclosed
US-6207783-B1 UNDERGROUND INSULATION CROMPTON CORPORATION 2001-03-27 US disclosed
US-6207720-B1 DISPERSING EMULSIFIER IN WATER; PREPARING AN OIL CONCENTRATE BY MIXING EMULSIFIER AND WATER BLEND WITHHYDROLYZABLE SILANE; SLOWLY ADDING WATER TO OIL CONCENTRATE UNTIL INVERSION OF OIL CONCENTRATE OCCURS CROMPTON CORPORATION 2001-03-27 US disclosed
WO-2001000309-A1 HYDROLYZABLE SILANE EMULSIONS AND METHOD FOR PREPARING THE SAME CROMPTON CORPORATION (US) 2001-01-04 WO disclosed
EP-0991698-A1 SILICONE OLIGOMERS AND CURABLE COMPOSITIONS CONTAINING SAME CK WITCO CORPORATION (US) 2000-04-12 EP disclosed
WO-1999054386-A1 SILICONE OLIGOMERS AND CURABLE COMPOSITIONS CONTAINING SAME WITCO CORPORATION (US) 1999-10-28 WO disclosed