SCHEMBL4616586

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4614621	0.82	MAPT (0.50)	MAPTALDH1A1KMT2AMEN1SMN1; SMN2
	SCHEMBL4616837	0.80	ALDH1A1 (0.45)	MAPTALDH1A1SMN1; SMN2MAPK1TDP1
	SCHEMBL19116731	0.79	MAPT (0.45)	ADORA3MAPTALDH1A1KMT2AMEN1
	SCHEMBL4617337	0.79	IDO1 (0.42)	MAPTALDH1A1KMT2AMEN1SMN1; SMN2
	SCHEMBL4614158	0.79	NPC1 (0.42)	ALDH1A1KMT2ATDP1KDM4ECA12
	SCHEMBL4616451	0.76	KMT2A (0.57)	ADORA3BACE1MAPTALDH1A1KMT2A
	SCHEMBL4615109	0.76	MAPT (0.51)	ADORA3MAPTALDH1A1KMT2AMEN1
	SCHEMBL5708491	0.72	MAPT (0.44)	ADORA3MAPTALDH1A1KMT2AMEN1
	SCHEMBL5708510	0.71	MAPT (0.46)	ADORA3MAPTALDH1A1KMT2AMEN1
	SCHEMBL5287532	0.71	MAPT (0.49)	ADORA3MAPTALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.