⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4619963 | 0.84 | P2RX3 (0.35) | — | |
| Pyrophosphoric Acid SCHEMBL381155 | 0.66 | KDM4E (0.30) | — | |
| Pyrophosphoric Acid SCHEMBL2935409 | 0.65 | KDM4E (0.49) | — | |
| Pyrophosphoric Acid SCHEMBL459236 | 0.59 | FDPS (0.42) | — | |
| Pyrophosphoric Acid SCHEMBL637333 | 0.57 | ALDH1A1 (0.35) | — | |
| SCHEMBL3787733 | 0.57 | — | — | |
| Pyrophosphoric Acid SCHEMBL3175309 | 0.55 | FDPS (0.53) | — | |
| Pyrophosphoric Acid SCHEMBL5997484 | 0.54 | FDPS (0.59) | — | |
| Pyrophosphoric Acid SCHEMBL27842647 | 0.53 | FDPS (0.91) | — | |
| Pyrophosphoric Acid SCHEMBL11418559 | 0.52 | MAPT (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240115221-A1 | POSITRON IMAGING TOMOGRAPHY IMAGING AGENT COMPOSITION ADN METHOD FOR BACTERIAL INFECTION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2024-04-11 | — | — | US | disclosed |
| US-11857352-B2 | Positron imaging tomography imaging agent composition and method for bacterial infection | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2024-01-02 | — | — | US | disclosed |
| US-20230226228-A1 | POSITRON IMAGING TOMOGRAPHY IMAGING AGENT COMPOSITION AND METHOD FOR DETECTION OF BACTERIAL INFECTION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2023-07-20 | — | — | US | disclosed |
| WO-2021226076-A1 | POSITRON IMAGING TOMOGRAPHY IMAGING AGENT COMPOSITION AND METHOD FOR DETECTION OF BACTERIAL INFECTION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2021-11-11 | — | — | WO | disclosed |
| US-20190209103-A1 | POSITRON IMAGING TOMOGRAPHY IMAGING AGENT COMPOSITION AND METHOD FOR BACTERIAL INFECTION | The Research Foundation for The State University o f New York (US) | 2019-07-11 | — | — | US | disclosed |
| EP-1887081-A2 | DNA Sequences | Ceres Incorporated (US) | 2008-02-13 | — | — | EP | disclosed |
| EP-1586645-A2 | Sequence-determined DNA fragments and corresponding polypeptides encoded thereby | Ceres Incorporated (US) | 2005-10-19 | — | — | EP | disclosed |
| EP-1059354-A2 | Sequence-determined DNA fragments and corresponding polypeptides encoded thereby | Ceres Incorporated (US) | 2000-12-13 | — | — | EP | disclosed |
| EP-1033405-A2 | Sequence-determined DNA fragments and corresponding polypeptides encoded thereby | Ceres Incorporated (US) | 2000-09-06 | — | — | EP | disclosed |