SCHEMBL46202

SCHEMBL46202

CCOC(=O)OC1=C(c2c(C)cc(Cl)cc2C)C(=O)N(C)C12CCN(OC)CC2

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
TSHR P16473 1/20 0.32
ALDH1A1 P00352 1/20 0.32
OPRM1 P35372 2/20 0.32
HTT P42858 1/20 0.32
HSD17B10 Q99714 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31
GABRA3 P34903 1/20 0.31
GABRA2 P47869 1/20 0.31
GABRB2 P47870 1/20 0.31
GABRA4 P48169 1/20 0.31
GABRA6 Q16445 1/20 0.31
POLB P06746 1/20 0.31
APP P05067 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38046 0.93 MEN1 (0.32) MEN1KMT2APOLB
SCHEMBL45958 0.91 MAPK1 (0.32) MEN1KMT2ATSHRALDH1A1GABRA1
SCHEMBL12071048 0.91 MEN1 (0.33) MEN1KMT2ATSHRALDH1A1OPRM1
SCHEMBL12072062 0.90 TSHR (0.32) MEN1KMT2ATSHROPRM1HTT
SCHEMBL46108 0.89 L3MBTL1 (0.31)
SCHEMBL45964 0.89 MEN1 (0.33) MEN1KMT2AALDH1A1OPRM1HTT
SCHEMBL45996 0.89 TSHR (0.32) TSHRALDH1A1OPRM1POLB
SCHEMBL29376984 0.89
SCHEMBL14998131 0.88 GABRA1 (0.33) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL15182369 0.88 GABRA1 (0.33) GABRA1GABRG2GABRB3GABRA5GABRA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1640 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4734762-A1 BAIT COMPOSITIONS FMC Corporation (US) 2026-05-06 EP claimed
EP-4723891-A1 USE OF RIBOFLAVIN AS A SEED TREATMENT Syngenta Crop Protection AG (CH) 2026-04-15 EP claimed
US-20260090546-A1 COMBINATIONS OF KETO-ENOL INSECTICIDES ADAMA MAKHTESHIM LTD. (IL) 2026-04-02 US claimed
EP-4712773-A1 PESTICIDAL MIXTURES COMPRISING A BENZAMIDE COMPOUND BASF SE (DE) 2026-03-25 EP claimed
EP-4709166-A1 NOVEL INSECTICIDAL MIXTURES FOR CONTROLLING AND PROTECTING CROPS ADAMA MAKHTESHIM LTD. (IL) 2026-03-18 EP claimed
EP-4710766-A1 MIXTURES OF AMBRUTICIN WITH AT LEAST ONE FURTHER PESTICIDE BASF SE (DE) 2026-03-18 EP claimed
WO-2026046760-A1 PESTICIDAL MIXTURES COMPRISING AN ETHYLSULFONE COMPOUND BASF SE (DE) 2026-03-05 WO claimed
EP-4114183-B1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2026-02-25 EP claimed
US-12532884-B2 Fungicidal compositions SYNGENTA CROP PROTECTION AG (CH) 2026-01-27 US claimed
US-20250380695-A1 INSECTICIDE FORMULATIONS WITH BUILT-IN ADJUVANTS ADAMA MAKHTESHIM LTD. (IL) 2025-12-18 US claimed
EP-3996508-A1 MIXTURES COMPRISING INDAZOLE PESTICIDES FMC Corporation (US) 2022-05-18 EP claimed
WO-2022073797-A1 MIXTURES CONTAINING CYCLOBUTRIFLURAM BASF SE (DE) 2022-04-14 WO claimed
EP-3978504-A1 CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDINE DERIVATIVES FOR COMBATING ANIMAL PESTS BASF SE (DE) 2022-04-06 EP claimed
WO-2022053640-A1 MIXTURES CONTAINING CALCIUM AND MAGNESIUM PHOSPHONATE AS PESTICIDES PRIMINGTEC UG (HAFTUNGSBESCHRÄNKT) (DE) 2022-03-17 WO claimed
EP-3952647-A1 PESTICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2022-02-16 EP claimed
US-20220041582-A1 ISOXAZOLINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS FMC CORPORATION 2022-02-10 US claimed
WO-2022023931-A1 A PESTICIDALLY ACTIVE MIXTURE COMPRISING PYRAZOLOPYRIDINE ANTHRANILAMIDE COMPOUND, OXIDES OR SALTS THEREOF PI INDUSTRIES LTD (IN) 2022-02-03 WO claimed
WO-2022018745-A1 AGROCHEMICAL MIXTURES OF DIAMIDES, PLANT HEALTH ADDITIVES AND INSECTICIDE RAJDHANI PETROCHEMICALS PRIVATE LIMITED (IN) 2022-01-27 WO claimed
EP-3518676-A1 PESTICIDAL MIXTURES BASF SE (DE) 2019-08-07 EP claimed
WO-2018059997-A1 PESTICIDAL MIXTURES BASF SE (DE) 2018-04-05 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220041582-A1 ISOXAZOLINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS PRDX1, CYP4X1, ACHE MEN1 3987/4885KMT2A 2112/4885TSHR 2717/4885
US-20260090546-A1 COMBINATIONS OF KETO-ENOL INSECTICIDES CYP11A1, CYP17A1, NR1H2 MEN1 2862/4885KMT2A 1034/4885TSHR 1121/4885
US-12532884-B2 Fungicidal compositions CYP4F3, CYP4X1, CYP4B1 MEN1 1715/4885KMT2A 1918/4885TSHR 1033/4885
US-20250380695-A1 INSECTICIDE FORMULATIONS WITH BUILT-IN ADJUVANTS CYP19A1, ACHE, KMO MEN1 2904/4885KMT2A 198/4885TSHR 1732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.