Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 3/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4365443 | 0.88 | CCKBR (0.49) | CCKBRMAPK14CPB2FAAHCNR2 | |
| SCHEMBL4623284 | 0.81 | FAAH (0.53) | CCKBRFAAHCNR2 | |
| SCHEMBL3589250 | 0.80 | PTPRC (0.52) | CCKBRMAPK14PTPRCCTSLPTPN13 | |
| SCHEMBL2249422 | 0.78 | HPGDS (0.59) | MAPK14PTPRCCTSLPTPN13 | |
| SCHEMBL4621604 | 0.77 | NPC1 (0.44) | CCKBRCPB2FAAH | |
| SCHEMBL2247337 | 0.77 | CCKBR (0.52) | CCKBRPTPRCCTSLPTPN13 | |
| SCHEMBL2247862 | 0.77 | CCKBR (0.51) | CCKBRPTPRCCTSLPTPN13 | |
| SCHEMBL3587576 | 0.74 | CCKBR (0.51) | CCKBR | |
| SCHEMBL2247265 | 0.72 | MMP2 (0.63) | PTPRCCTSLPTPN13 | |
| SCHEMBL2249427 | 0.71 | CA2 (0.59) | MAPK14PTPRCCTSLPTPN13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902014-A2 | GLUTAMATE AGGRECANASE INHIBITORS | Wyeth (US) | 2008-03-26 | — | — | EP | claimed |
| WO-2007008994-A2 | GLUTAMATE AGGRECANASE INHIBITORS | WYETH (US) | 2007-01-18 | — | — | WO | claimed |