Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PYCR1 | P32322 | 7/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4622686 | 0.90 | KCNH2 (0.41) | KCNH2LMNAPYCR1MMP2MMP12 | |
| SCHEMBL13259162 | 0.81 | KDM4E (0.51) | HTTKCNH2LMNAKDM4EMMP2 | |
| SCHEMBL9209153 | 0.79 | KCNH2 (0.41) | HTTL3MBTL1KCNH2LMNAPYCR1 | |
| SCHEMBL17971132 | 0.76 | PYCR1 (0.38) | HTTL3MBTL1LMNAPYCR1KDM4E | |
| SCHEMBL25864597 | 0.75 | CYP3A4 (0.41) | KCNH2LMNAPYCR1MMP2HPGD | |
| SCHEMBL81530 | 0.71 | MMP2 (0.47) | HTTL3MBTL1LMNAPYCR1KDM4E | |
| SCHEMBL17757994 | 0.71 | IDO1 (0.48) | PYCR1MAOBMAOAHTR2A | |
| SCHEMBL26675160 | 0.70 | PYCR1 (0.37) | KCNH2LMNAPYCR1 | |
| SCHEMBL18894300 | 0.70 | APP (0.56) | KCNH2MMP2MMP12 | |
| SCHEMBL3805100 | 0.70 | CA12 (0.53) | PYCR1HPGDMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219657-B1 | POLYARYLENE AND METHOD FOR PRODUCTION THEREOF | JAPAN SCIENCE & TECH AGENCY (JP) | 2008-03-19 | — | — | EP | disclosed |