Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4622686 | 0.78 | KCNH2 (0.41) | PYCR1KCNH2ACACBLMNA | |
| SCHEMBL9209153 | 0.76 | KCNH2 (0.41) | PYCR1KCNH2ACACBLMNA | |
| SCHEMBL4623625 | 0.70 | HTT (0.37) | PYCR1KCNH2LMNA | |
| SCHEMBL508102 | 0.69 | PYCR1 (0.41) | PYCR1KCNH2ACACBLMNA | |
| SCHEMBL9158372 | 0.68 | GABRP (0.44) | PYCR1KCNH2ACACB | |
| SCHEMBL4621099 | 0.67 | PYCR1 (0.40) | PYCR1ACACBLMNA | |
| SCHEMBL22122003 | 0.67 | CYP2C19 (0.60) | PYCR1ACACBLMNA | |
| SCHEMBL13997198 | 0.67 | PYCR1 (0.47) | PYCR1ACACBLMNA | |
| SCHEMBL797749 | 0.67 | FFAR1 (0.40) | PYCR1ACACBLMNA | |
| SCHEMBL81530 | 0.67 | MMP2 (0.47) | PYCR1ACACBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339884-A1 | Triazole N-Linked Carbamoyl Cyclohexyl Acids as LPA Antagonists | BRISTOL MYERS SQUIBB CO (US) | 2023-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339884-A1 | Triazole N-Linked Carbamoyl Cyclohexyl Acids as LPA Antagonists | LPAR3, LPAR1, LPAR2 | PYCR1 4076/4885KCNH2 3436/4885ACACB 831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.