SCHEMBL4623931

SCHEMBL4623931

C(=Cc1cccc(Nc2nc(Nc3ccccc3)nc(N3CCOCC3)n2)c1Nc1nc(Nc2ccccc2)nc(N2CCOCC2)n1)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.60
HTT P42858 2/20 0.60
POLB P06746 4/20 0.54
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA9 Q16790 1/20 0.52
MAPT P10636 7/20 0.51
KMT2A Q03164 7/20 0.51
TP53 P04637 1/20 0.51
MEN1 O00255 4/20 0.48
GAA P10253 4/20 0.48
CYP1A2 P05177 2/20 0.48
CYP3A4 P08684 2/20 0.48
CYP2C9 P11712 2/20 0.48
CYP2C19 P33261 2/20 0.48
PIKFYVE Q9Y2I7 1/20 0.48
NPSR1 Q6W5P4 2/20 0.47
RECQL P46063 1/20 0.47
TDP1 Q9NUW8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18796549 0.92 LMNA (0.65) LMNAHTTPOLBCA12CA1
SCHEMBL7778456 0.84 DDX3X (0.46) LMNAHTTCA12CA1CA2
SCHEMBL757098 0.83 LMNA (0.77) LMNAHTTPOLBCA12CA1
SCHEMBL3115297 0.83 LMNA (0.77) LMNAHTTPOLBCA12CA1
SCHEMBL30139086 0.83 LMNA (0.77) LMNAHTTPOLBCA12CA1
SCHEMBL8925967 0.82 LMNA (0.75) LMNAHTTPOLBCA12CA1
SCHEMBL3880764 0.82 LMNA (0.75) LMNAHTTPOLBCA12CA1
SCHEMBL1735430 0.82 LMNA (0.75) LMNAHTTPOLBCA12CA1
SCHEMBL27531940 0.82 LMNA (0.64) LMNAHTTPOLBCA12CA1
SCHEMBL10481518 0.81 LMNA (0.59) LMNAHTTPOLBCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111183214-B Leuco colorants as bluing agents in laundry care compositions 宝洁公司 2022-06-14 CN disclosed
CN-111183215-B Laundry care compositions and methods for determining their age 宝洁公司 2022-03-15 CN disclosed
CN-111247236-A Method for using leuco colorants as bluing agents in laundry care compositions 宝洁公司 2020-06-05 CN disclosed
CN-111183215-A Laundry care compositions and methods for determining their age 宝洁公司 2020-05-19 CN disclosed
CN-111183214-A Leuco colorants as bluing agents in laundry care compositions 宝洁公司 2020-05-19 CN disclosed
CN-111183216-A Method for using leuco colorants as bluing agents in laundry care compositions 宝洁公司 2020-05-19 CN disclosed
CN-111148825-A Method for using leuco colorants as bluing agents in laundry care compositions 宝洁公司 2020-05-12 CN disclosed
US-9862835-B2 Window coating WindowAlert, Inc. (US) 2018-01-09 US disclosed
US-20140037838-A1 WINDOW COATING WindowAlert, Inc. (US) 2014-02-06 US disclosed
EP-1904618-A1 A PACKAGED PRODUCT FOR MULTI-PHASE LAUNDRY TABLETS Unilever PLC (GB) 2008-04-02 EP disclosed
EP-1133549-A1 DETERGENT COMPOSITIONS UNILEVER PLC (GB) 2001-09-19 EP disclosed
WO-2001038478-A1 DETERGENT COMPOSITIONS UNILEVER N.V. (NL) 2001-05-31 WO disclosed
WO-2001038479-A1 DETERGENT COMPOSITIONS UNILEVER N.V. (NL) 2001-05-31 WO disclosed
WO-2000044869-A1 DETERGENT TABLETS UNILEVER PLC (GB) 2000-08-03 WO disclosed
WO-2000032741-A1 DETERGENT COMPOSITIONS UNILEVER PLC (GB) 2000-06-08 WO disclosed
US-6051545-A COMPACTED TABLET; MIXTURE OF SURFACTANT, BUILDER AND POLYMER LEVER BROTHERS COMPANY DIVISION OF CONOPCO, INC. (US) 2000-04-18 US disclosed
EP-0672104-B1 PROTECTION OF ADJUNCTS UNILEVER PLC (GB) 1997-07-02 EP disclosed
US-5480575-A IN A BIOPOLYMER; BLEACH CATALYSTS/PRECURSORS, BLEACH PRECURSORS; NON-AQUEOUS LIQUID DETERGENTS LEVER BROTHERS, DIVISION OF CONOPCO, INC. (US) 1996-01-02 US disclosed
EP-0672104-A1 PROTECTION OF ADJUNCTS. UNILEVER PLC (GB) 1995-09-20 EP disclosed
WO-1994012613-A1 PROTECTION OF ADJUNCTS UNILEVER PLC (GB) 1994-06-09 WO disclosed