SCHEMBL4625876

SCHEMBL4625876

CC(C)(C)O[Si](Oc1ccc(C(=O)c2ccc(O[Si](OC(C)(C)C)(c3ccccc3)c3ccccc3)cc2)cc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ELANE P08246 11/20 0.49
GAA P10253 1/20 0.43
PPARA Q07869 2/20 0.43
SRD5A2 P31213 1/20 0.42
PPARG P37231 2/20 0.40
FABP2 P12104 1/20 0.40
SLC22A12 Q96S37 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4627743 0.98 ELANE (0.51) ELANEGAAPPARASRD5A2PPARG
SCHEMBL5053991 0.84 MEN1 (0.47) GAAPPARG
SCHEMBL14230792 0.80 MAPT (0.41) ELANE
SCHEMBL4625644 0.80 NR1H2 (0.35)
SCHEMBL17070013 0.80 ELANE (0.54) ELANEGAAPPARASRD5A2PPARG
SCHEMBL4626091 0.80 ALDH1A1 (0.35)
SCHEMBL4625906 0.79 CYP19A1 (0.37)
SCHEMBL4625813 0.79 CYP19A1 (0.37)
SCHEMBL4624707 0.75 AHR (0.43)
SCHEMBL4626920 0.75 AHR (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1401851-B1 TWO-STAGE PROTECTIVE GROUPS FOR THE SYNTHESIS OF BIOPOLYMERS FEBIT BIOTECH GMBH (DE) 2008-07-02 EP disclosed
US-7355036-B2 Two-stage protective groups for the synthesis of biopolymers FEBIT AG (DE) 2008-04-08 US disclosed
US-20040197851-A1 Two-stage protective groups for the synthesis of biopolymers MR. CHRISTOPHER SEAGON, ESQ. (DE) 2004-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040197851-A1 Two-stage protective groups for the synthesis of biopolymers CTRB2, OGG1, CPB2 ELANE 1493/4885GAA 659/4885PPARA 3700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.