SCHEMBL4627743

SCHEMBL4627743

CC(C)(C)O[Si](Oc1ccc(C(=O)c2ccccc2)cc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ELANE P08246 11/20 0.51
GAA P10253 1/20 0.45
PPARA Q07869 1/20 0.45
PPARG P37231 1/20 0.42
STS P08842 1/20 0.42
SRD5A2 P31213 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4625876 0.98 ELANE (0.49) ELANEGAAPPARAPPARGSRD5A2
SCHEMBL5053991 0.82 MEN1 (0.47) GAAPPARGSTSALDH1A1TDP1
SCHEMBL17070013 0.82 ELANE (0.54) ELANEGAAPPARAPPARGSTS
SCHEMBL4625644 0.79 NR1H2 (0.35) ALDH1A1TDP1
SCHEMBL4626091 0.78 ALDH1A1 (0.35) ALDH1A1TSHRTDP1
SCHEMBL4625906 0.78 CYP19A1 (0.37) ALDH1A1TDP1
SCHEMBL4625813 0.78 CYP19A1 (0.37) ALDH1A1TDP1
SCHEMBL5280416 0.75 ELANE (0.57) ELANEGAAPPARAPPARGSTS
SCHEMBL4624707 0.74 AHR (0.43) ALDH1A1
SCHEMBL4626920 0.74 AHR (0.43) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1401851-B8 TWO-STAGE PROTECTIVE GROUPS FOR THE SYNTHESIS OF BIOPOLYMERS FEBIT HOLDING GMBH (DE) 2008-09-10 EP disclosed
EP-1401851-B1 TWO-STAGE PROTECTIVE GROUPS FOR THE SYNTHESIS OF BIOPOLYMERS FEBIT BIOTECH GMBH (DE) 2008-07-02 EP disclosed
US-7355036-B2 Two-stage protective groups for the synthesis of biopolymers FEBIT AG (DE) 2008-04-08 US disclosed
US-20040197851-A1 Two-stage protective groups for the synthesis of biopolymers MR. CHRISTOPHER SEAGON, ESQ. (DE) 2004-10-07 US disclosed
EP-1401851-A1 TWO-STAGE PROTECTIVE GROUPS FOR THE SYNTHESIS OF BIOPOLYMERS Febit AG (DE) 2004-03-31 EP disclosed
WO-2003004510-A1 TWO-STAGE PROTECTIVE GROUPS FOR THE SYNTHESIS OF BIOPOLYMERS FEBIT AG (DE) 2003-01-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040197851-A1 Two-stage protective groups for the synthesis of biopolymers CTRB2, OGG1, CPB2 ELANE 1493/4885GAA 659/4885PPARA 3700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.