SCHEMBL4632121

SCHEMBL4632121

Cc1cc(C)c(/C(=C\CO)c2ccccc2)c(C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 1/20 0.37
MTNR1B P49286 1/20 0.37
KMT2A Q03164 6/20 0.36
MEN1 O00255 5/20 0.36
LMNA P02545 3/20 0.36
MAPT P10636 2/20 0.36
RAB9A P51151 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
SLC6A1 P30531 1/20 0.36
SLC6A2 P23975 2/20 0.36
SLC6A4 P31645 2/20 0.36
SLC6A3 Q01959 2/20 0.36
HPGD P15428 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NPC1 O15118 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4632123 1.00 MTNR1A (0.37) MTNR1AMTNR1BKMT2AMEN1LMNA
SCHEMBL10957132 0.98 MTNR1A (0.36) MTNR1AMTNR1BKMT2AMEN1LMNA
SCHEMBL4630818 0.83 LMNA (0.33) KMT2AMEN1LMNAMAPTNPSR1
SCHEMBL3844699 0.79 KMT2A (0.38) KMT2AMEN1LMNAMAPTRAB9A
SCHEMBL3844702 0.79 KMT2A (0.38) KMT2AMEN1LMNAMAPTRAB9A
SCHEMBL4631622 0.78 NPC1 (0.50) MTNR1AMTNR1BKMT2AMEN1LMNA
SCHEMBL4631618 0.78 NPC1 (0.50) MTNR1AMTNR1BKMT2AMEN1LMNA
SCHEMBL4630812 0.77 MTNR1A (0.48) MTNR1AMTNR1BNPSR1CHRNB2CHRNB4
SCHEMBL1790148 0.75 SLC6A1 (0.44) MTNR1AMTNR1BKMT2AMEN1LMNA
SCHEMBL17295886 0.73 CES2 (0.41) KMT2AMEN1LMNAMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1927889-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2014-06-25 EP disclosed
EP-1927889-A1 Lithographic printing plate precursor FUJIFILM Corporation (JP) 2008-06-04 EP disclosed
EP-1091253-B1 Plate making process for planographic plate, automatic developing apparatus and recording medium FUJI PHOTO FILM CO LTD (JP) 2005-03-30 EP disclosed
US-6558873-B1 Interlayer containing a compound capable of forming a complex with aluminum and a photopolymerizable photosensitive layer containing a photopolymerization initiator, an addition polymerizable compound capable of complexing with aluminum FUJI PHOTO FILM CO., LTD. (JP) 2003-05-06 US disclosed
EP-1091253-A2 Plate making process for planographic plate, automatic developing apparatus and recording medium FUJI PHOTO FILM CO., LTD. (JP) 2001-04-11 EP disclosed
EP-1091251-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-04-11 EP disclosed
US-4687727-A Light-sensitive planographic printing plate with layer of diazo resin containing photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1987-08-18 US disclosed