SCHEMBL4630818

SCHEMBL4630818

Cc1cc(C)c(C(=CCO)c2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.33
KDM4E B2RXH2 3/20 0.33
HPGD P15428 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALDH1A1 P00352 3/20 0.32
MAPT P10636 2/20 0.32
GAA P10253 2/20 0.32
RAPGEF4 Q8WZA2 1/20 0.32
MAPK1 P28482 1/20 0.32
TAS1R3 Q7RTX0 2/20 0.31
TAS1R1 Q7RTX1 2/20 0.31
TAS1R2 Q8TE23 2/20 0.31
TP53 P04637 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
MCOLN3 Q8TDD5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10957132 0.86 MTNR1A (0.36) LMNAHPGDL3MBTL1MEN1KMT2A
SCHEMBL4632121 0.83 MTNR1A (0.37) LMNAHPGDL3MBTL1MEN1KMT2A
SCHEMBL10604733 0.75 RAPGEF4 (0.38) LMNAKDM4EHPGDL3MBTL1MEN1
SCHEMBL3851487 0.71 RAPGEF4 (0.35) LMNAKDM4EHPGDL3MBTL1MEN1
SCHEMBL5595817 0.67 LMNA (0.32) LMNAKDM4EALDH1A1MAPTGAA
SCHEMBL2848308 0.66 RAPGEF4 (0.43) LMNAKDM4EHPGDL3MBTL1MEN1
SCHEMBL6419890 0.65 ALDH1A1 (0.43) LMNAHPGDMEN1KMT2ASMN1; SMN2
SCHEMBL8412772 0.65 ALDH1A1 (0.47) LMNAKDM4EHPGDL3MBTL1MEN1
SCHEMBL918994 0.64 RAPGEF4 (0.41) LMNAKDM4EHPGDL3MBTL1MEN1
SCHEMBL2722808 0.64 RAPGEF4 (0.41) LMNAKDM4EHPGDL3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1927889-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2014-06-25 EP disclosed
EP-1927889-A1 Lithographic printing plate precursor FUJIFILM Corporation (JP) 2008-06-04 EP disclosed
EP-1091253-B1 Plate making process for planographic plate, automatic developing apparatus and recording medium FUJI PHOTO FILM CO LTD (JP) 2005-03-30 EP disclosed
US-6558873-B1 Interlayer containing a compound capable of forming a complex with aluminum and a photopolymerizable photosensitive layer containing a photopolymerization initiator, an addition polymerizable compound capable of complexing with aluminum FUJI PHOTO FILM CO., LTD. (JP) 2003-05-06 US disclosed
EP-1091253-A2 Plate making process for planographic plate, automatic developing apparatus and recording medium FUJI PHOTO FILM CO., LTD. (JP) 2001-04-11 EP disclosed
EP-1091251-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-04-11 EP disclosed
US-4687727-A Light-sensitive planographic printing plate with layer of diazo resin containing photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1987-08-18 US disclosed
EP-0104863-A2 Light-sensitive planographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1984-04-04 EP disclosed