Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NMBR | P28336 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4632718 | 0.83 | ALOX5 (0.43) | GPR84ALOX5EPHX2MEN1KMT2A | |
| SCHEMBL4632723 | 0.79 | ALOX5 (0.41) | GPR84ALOX5EPHX2MEN1KMT2A | |
| SCHEMBL4632727 | 0.79 | ALOX5 (0.41) | GPR84ALOX5EPHX2MEN1KMT2A | |
| SCHEMBL4028879 | 0.78 | ALOX5 (0.47) | GPR84ALOX5EPHX2MEN1KMT2A | |
| SCHEMBL4034817 | 0.78 | ALOX5 (0.46) | GPR84ALOX5EPHX2MEN1KMT2A | |
| SCHEMBL5149351 | 0.77 | ANO1 (0.41) | MEN1KMT2AKDM4EMAPK1CYP2D6 | |
| SCHEMBL4038448 | 0.77 | KMT2A (0.42) | MEN1KMT2ANMBRKDM4EMAPT | |
| SCHEMBL4633386 | 0.76 | HDAC3 (0.44) | MEN1KMT2AMAPT | |
| SCHEMBL4039235 | 0.75 | ALOX5 (0.44) | GPR84ALOX5EPHX2MEN1KMT2A | |
| SCHEMBL4034576 | 0.75 | ALOX5 (0.52) | ALOX5EPHX2MEN1KMT2ANMBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1932831-A1 | 1,2-Diarylacetylene Derivatives of Acyltryptophanols | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-06-18 | — | — | EP | disclosed |