Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 2/20 | 0.36 |
| ▸ | STAT3 | P40763 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4157950 | 0.88 | RORC (0.37) | STAT3SLC7A5RORCGABRA1GABRG2 | |
| SCHEMBL4636561 | 0.86 | NOTUM (0.39) | PYGLSTAT3CES2BCHECES1 | |
| SCHEMBL4637507 | 0.77 | RXFP1 (0.35) | CES2BCHECES1ALDH1A1KAT6A | |
| SCHEMBL4637632 | 0.75 | CES2 (0.33) | CES2BCHECES1ALDH1A1KAT6A | |
| SCHEMBL4636733 | 0.74 | CES2 (0.33) | CES2BCHECES1KAT6A | |
| SCHEMBL4150844 | 0.74 | SLC7A5 (0.40) | SLC7A5RORCGABRA1GABRG2GABRB3 | |
| SCHEMBL4154212 | 0.73 | NOTUM (0.41) | STAT3RORCKMT2ARAB9A | |
| SCHEMBL4636754 | 0.73 | ALDH1A1 (0.32) | CES2BCHECES1ALDH1A1KAT6A | |
| SCHEMBL4636520 | 0.73 | KAT6A (0.38) | CES2BCHECES1KAT6APOLB | |
| SCHEMBL4636303 | 0.72 | KAT6A (0.31) | CES2BCHECES1KAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937629-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007046513-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-26 | — | — | WO | disclosed |