Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4154212 | 0.87 | NOTUM (0.41) | NOTUMSTAT3KMT2ACA12CA1 | |
| SCHEMBL4636285 | 0.86 | PYGL (0.36) | STAT3CES2BCHECES1ALDH1A1 | |
| SCHEMBL4157950 | 0.73 | RORC (0.37) | STAT3KMT2ALMNARAB9A | |
| SCHEMBL27864444 | 0.73 | CES2 (0.55) | CES2BCHECES1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL28306201 | 0.72 | CES2 (0.53) | CES2BCHECES1ALDH1A1KMT2A | |
| SCHEMBL2338866 | 0.69 | NOTUM (0.51) | NOTUMALDH1A1CA12CA1CA2 | |
| SCHEMBL4912349 | 0.68 | TLR7 (0.46) | KMT2AHDAC8HPGDNPC1TLR7 | |
| SCHEMBL11372591 | 0.68 | KMT2A (0.41) | CES2CES1KMT2AMAPTTLR7 | |
| SCHEMBL3688381 | 0.67 | ALDH1A1 (0.55) | NOTUMALDH1A1KMT2ACA12CA1 | |
| SCHEMBL28821060 | 0.67 | CES2 (0.50) | CES2BCHECES1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937629-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007046513-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-26 | — | — | WO | disclosed |