Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 11/20 | 0.66 |
| ▸ | PDE7B | Q9NP56 | 5/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.62 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.57 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29484401 | 0.85 | TXNRD1 (0.67) | POLBBCL2L1GSTP1GSTM2LMNA | |
| SCHEMBL4003277 | 0.85 | LMNA (0.68) | POLBBCL2L1GSTP1GSTM2LMNA | |
| SCHEMBL1645182 | 0.85 | TXNRD1 (0.67) | POLBBCL2L1GSTP1GSTM2LMNA | |
| SCHEMBL3407545 | 0.85 | PDE7A (0.60) | PDE7APDE7BPOLBBCL2L1LMNA | |
| SCHEMBL2028311 | 0.84 | SLC6A2 (0.68) | PDE7APOLBBCL2L1GSTP1GSTM2 | |
| SCHEMBL17080274 | 0.84 | LMNA (0.63) | PDE7APDE7BPOLBBCL2L1GSTP1 | |
| SCHEMBL1645800 | 0.84 | MAPT (0.60) | PDE7APDE7BPOLBBCL2L1GSTP1 | |
| SCHEMBL1645181 | 0.84 | SLC6A4 (0.75) | POLBBCL2L1GSTP1GSTM2LMNA | |
| SCHEMBL4001367 | 0.84 | GSTP1 (0.57) | PDE7APDE7BPOLBBCL2L1GSTP1 | |
| SCHEMBL3174865 | 0.84 | GSTP1 (0.57) | PDE7APDE7BPOLBBCL2L1GSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937614-A1 | IRON CATALYZED CROSS-COUPLING REACTIONS OF IMIDOYL DERIVATIVES | Arcadia Pharmaceuticals Inc. (US) | 2008-07-02 | — | — | EP | disclosed |
| US-20070106074-A1 | Iron catalyzed cross-coupling reactions of imidoyl derivatives | ACADIA PHARMACEUTICALS | 2007-05-10 | — | — | US | disclosed |
| WO-2007047776-A1 | IRON CATALYZED CROSS-COUPLING REACTIONS OF IMIDOYL DERIVATIVES | ACADIA PHARMACEUTICALS INC. (US) | 2007-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070106074-A1 | Iron catalyzed cross-coupling reactions of imidoyl derivatives | SDHB, TFRC, SLC40A1 | PDE7A 4861/4885PDE7B 4581/4885POLB 1159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.