Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7144417 | 0.79 | HTR6 (0.52) | HTR6METALDH1A1AKR1B1KMT2A | |
| SCHEMBL4606513 | 0.79 | HTR6 (0.47) | HTR6METALDH1A1AKR1B1HTT | |
| SCHEMBL5224094 | 0.76 | NPSR1 (0.45) | HTR6METALDH1A1AKR1B1HTT | |
| SCHEMBL9801800 | 0.74 | PPARA (0.43) | ALDH1A1KIF18AKMT2AGAANPSR1 | |
| SCHEMBL17397967 | 0.69 | HTR6 (0.46) | HTR6ALDH1A1HSD17B10TDP1HTT | |
| SCHEMBL7948044 | 0.69 | MET (0.51) | HTR6METALDH1A1HSD17B10TDP1 | |
| SCHEMBL8080841 | 0.69 | HTR6 (0.72) | HTR6ALDH1A1HSD17B10TDP1HTT | |
| SCHEMBL516500 | 0.69 | HSD11B1 (0.67) | HTR6ALDH1A1HSD17B10TDP1AKR1B1 | |
| SCHEMBL16882344 | 0.68 | HTR6 (0.45) | HTR6ALDH1A1HSD17B10TDP1AKR1B1 | |
| SCHEMBL23291552 | 0.68 | HTR6 (0.45) | HTR6ALDH1A1HSD17B10TDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937645-A1 | PYRAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007045868-A1 | PYRAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2007-04-26 | — | — | WO | disclosed |