SCHEMBL9801800

SCHEMBL9801800

O=C(c1ccc(Cl)cc1)c1n[nH]cc1S(=O)(=O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 1/20 0.43
HSD11B1 P28845 2/20 0.43
NR4A1 P22736 1/20 0.40
KMT2A Q03164 4/20 0.40
MEN1 O00255 3/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NPSR1 Q6W5P4 2/20 0.39
LMNA P02545 1/20 0.39
ALDH1A1 P00352 3/20 0.38
MAPT P10636 2/20 0.38
KDM4E B2RXH2 2/20 0.38
MAPK1 P28482 1/20 0.38
ENPP3 O14638 1/20 0.38
ENPP1 P22413 1/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
SRD5A2 P31213 1/20 0.38
GAA P10253 1/20 0.38
PKM P14618 1/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5224094 0.80 NPSR1 (0.45) NPSR1LMNAALDH1A1KDM4EGAA
SCHEMBL4637602 0.74 HTR6 (0.45) KMT2ANPSR1LMNAALDH1A1KDM4E
SCHEMBL9801787 0.71 HSD11B1 (0.43) PPARAHSD11B1NR4A1KMT2AMEN1
SCHEMBL9475034 0.68 MAPK1 (0.70) KMT2AMEN1SMN1; SMN2LMNAALDH1A1
SCHEMBL5527337 0.68 MAPK1 (0.70) KMT2AMEN1SMN1; SMN2LMNAALDH1A1
SCHEMBL7144417 0.67 HTR6 (0.52) KMT2ALMNAALDH1A1KDM4EGAA
SCHEMBL4606513 0.67 HTR6 (0.47) KMT2AMEN1SMN1; SMN2LMNAALDH1A1
SCHEMBL13309933 0.67 ITGA1 (0.54) LMNAKDM4EMAPK1SRD5A2KIF18A
SCHEMBL11451249 0.67 MMP2 (0.47) PPARAKMT2AMEN1LMNAALDH1A1
SCHEMBL6302201 0.66 MAPK1 (0.47) KMT2AMEN1LMNAMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0417556-A2 Positive-working radiation-sensitive mixture and recording material prepared therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1991-03-20 EP disclosed