Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.38 |
| ▸ | VNN1 | O95497 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4637822 | 0.94 | ALDH1A1 (0.43) | ADORA3PTGER4POLBAKR1C3AKR1C2 | |
| SCHEMBL4638478 | 0.89 | ADORA3 (0.41) | ADORA3PTGER4POLBAKR1C3AKR1C2 | |
| SCHEMBL4637820 | 0.85 | GAA (0.40) | ADORA3PTGER4POLBAKR1C3AKR1C2 | |
| SCHEMBL4638051 | 0.84 | ALDH1A1 (0.39) | ADORA3PTGER4AKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL4638558 | 0.83 | ALDH1A1 (0.42) | ADORA3PTGER4POLBAKR1C3AKR1C2 | |
| SCHEMBL4637775 | 0.81 | POLB (0.45) | ADORA3PTGER4POLBAKR1C3AKR1C2 | |
| SCHEMBL4637826 | 0.79 | ALDH1A1 (0.47) | ADORA3PTGER4POLBAKR1C3AKR1C2 | |
| SCHEMBL4637811 | 0.78 | GRM2 (0.36) | ADORA3PTGER4AKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL4638520 | 0.77 | ALDH1A1 (0.44) | POLBAKR1C3AKR1C2ALDH1A1GAA | |
| SCHEMBL4638481 | 0.76 | IDH1 (0.44) | GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501808-B1 | TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-07-02 | — | — | EP | disclosed |