SCHEMBL46390

SCHEMBL46390

CC(C)(CCO)Oc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
RECQL P46063 1/20 0.43
PPARA Q07869 6/20 0.40
PPARG P37231 6/20 0.38
LTA4H P09960 1/20 0.36
CA4 P22748 1/20 0.36
LMNA P02545 2/20 0.35
RIPK1 Q13546 1/20 0.35
CYP2D6 P10635 1/20 0.35
ALOX15 P16050 1/20 0.34
SLC6A2 P23975 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
MEN1 O00255 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
KMT2A Q03164 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
PPARD Q03181 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19427824 0.89 ALDH1A1 (0.40) ALDH1A1RECQLPPARAPPARGLTA4H
SCHEMBL28141859 0.87 CA4 (0.42) ALDH1A1PPARAPPARGLTA4HCA4
SCHEMBL11613159 0.83 CA4 (0.36) ALDH1A1PPARAPPARGLTA4HCA4
SCHEMBL1757874 0.83 ALDH1A1 (0.41) ALDH1A1RECQLPPARAPPARGLTA4H
SCHEMBL26277295 0.81 ABL1 (0.36) ALDH1A1RECQLPPARAPPARGLMNA
SCHEMBL1452863 0.81 LTA4H (0.39) PPARAPPARGLTA4HCA4RIPK1
Ethylene Glycol SCHEMBL5936849 0.80 ALDH1A1 (0.41) ALDH1A1RECQLPPARAPPARGLTA4H
SCHEMBL23468940 0.80 CYP1A2 (0.46) ALDH1A1PPARAPPARGNPC1RAB9A
SCHEMBL7604507 0.80 ACHE (0.46) ALDH1A1RECQLLMNAKMT2A
SCHEMBL14767356 0.79 ALDH1A1 (0.39) ALDH1A1RECQLPPARAPPARGLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113891882-B Process for producing dihydroisoxazole 组合化学工业株式会社 2024-11-26 CN disclosed
CN-113891882-A Method for producing dihydroisoxazole 组合化学工业株式会社 2022-01-04 CN disclosed
WO-2020251006-A1 METHOD FOR PRODUCING DIHYDROISOXAZOLE クミアイ化学工業株式会社 2020-12-17 WO disclosed
EP-1502941-B1 Image-forming method and developer FUJIFILM CORP (JP) 2015-12-23 EP disclosed
US-20120277275-A1 AZOLE AND THIAZOLE DERIVATIVES AND THEIR USE PULMAGEN THERAPEUTICS (SYNERGY) LIMITED (GB) 2012-11-01 US disclosed
US-20120277275-A1 AZOLE AND THIAZOLE DERIVATIVES AND THEIR USE PULMAGEN THERAPEUTICS (SYNERGY) LIMITED (GB) 2012-11-01 US disclosed
US-20120277275-A1 AZOLE AND THIAZOLE DERIVATIVES AND THEIR USE PULMAGEN THERAPEUTICS (SYNERGY) LIMITED (GB) 2012-11-01 US disclosed
WO-2011146604-A2 OPTICAL BRIGHTENERS AND COMPOSITIONS COMPRISING THE SAME MILLIKEN & COMPANY (US) 2011-11-24 WO disclosed
EP-1400852-B1 Photopolymerizable presensitized plate and method for making lithographic printing plate FUJIFILM CORP (JP) 2011-07-06 EP disclosed
EP-2280006-A1 PHARMACEUTICAL COMPOSITION FOR INHALATION COMPRISING AN OXAZOLE OR THIAZOLE M3 MUSCARINIC RECEPTOR ANTAGONIST Pulmagen Therapeutics (Synergy) Limited (GB) 2011-02-02 EP disclosed
EP-2280006-A1 PHARMACEUTICAL COMPOSITION FOR INHALATION COMPRISING AN OXAZOLE OR THIAZOLE M3 MUSCARINIC RECEPTOR ANTAGONIST Pulmagen Therapeutics (Synergy) Limited (GB) 2011-02-02 EP disclosed
EP-1253472-B1 Alkaline developer for lithographic printing plate and method for preparing lithographic printing plate FUJIFILM CORP (JP) 2010-12-01 EP disclosed
EP-1924570-B1 AZOLE AND THIAZOLE DERIVATIVES AND THEIR USE PULMAGEN THERAPEUTICS SYNERGY (GB) 2010-10-20 EP disclosed
EP-1924570-B1 AZOLE AND THIAZOLE DERIVATIVES AND THEIR USE PULMAGEN THERAPEUTICS SYNERGY (GB) 2010-10-20 EP disclosed
US-20100113540-A1 Azole and Thiazole Derivatives and Their Use ARGENTA DISCOVERY LIMITED (GB) 2010-05-06 US disclosed
US-20100113540-A1 Azole and Thiazole Derivatives and Their Use ARGENTA DISCOVERY LIMITED (GB) 2010-05-06 US disclosed
US-20100113540-A1 Azole and Thiazole Derivatives and Their Use ARGENTA DISCOVERY LIMITED (GB) 2010-05-06 US disclosed
EP-1273971-B1 Process for photopolymerization by exposure of a photosensitive lithographic printing plate FUJIFILM CORP (JP) 2010-02-10 EP disclosed
WO-2007017669-A1 AZOLE AND THIAZOLE DERIVATIVES AND THEIR USE ARGENTA DISCOVERY LTD. (GB) 2007-02-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100113540-A1 Azole and Thiazole Derivatives and Their Use CHRM3, CHRM2, CHRM1 ALDH1A1 2263/4885RECQL 4142/4885PPARA 325/4885
US-20120277275-A1 AZOLE AND THIAZOLE DERIVATIVES AND THEIR USE CHRM3, GPR65, GPR34 ALDH1A1 900/4885RECQL 3656/4885PPARA 309/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.