Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 6/20 | 0.64 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.51 |
| ▸ | CTSG | P08311 | 1/20 | 0.51 |
| ▸ | CMA1 | P23946 | 1/20 | 0.51 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31244 | 0.92 | SOS1 (0.64) | PGRSOS1TDP1ALDH1A1HSD17B10 | |
| SCHEMBL9536733 | 0.92 | SOS1 (0.64) | PGRSOS1TDP1ALDH1A1HSD17B10 | |
| SCHEMBL1133769 | 0.92 | PGR (0.53) | PGRSOS1NR3C1TDP1ALDH1A1 | |
| SCHEMBL3114864 | 0.88 | PGR (0.62) | PGRSOS1NR3C1TDP1HTT | |
| SCHEMBL8124976 | 0.87 | MMP1 (0.49) | PGRSOS1NR3C1ALDH1A1HTT | |
| SCHEMBL7892614 | 0.87 | SOS1 (0.58) | PGRSOS1TDP1ALDH1A1HSD17B10 | |
| SCHEMBL9720036 | 0.84 | HTT (0.58) | PGRSOS1TDP1ALDH1A1HSD17B10 | |
| SCHEMBL433497 | 0.84 | HTT (0.58) | PGRSOS1TDP1ALDH1A1HSD17B10 | |
| SCHEMBL9539212 | 0.83 | ALDH1A1 (0.56) | PGRSOS1TDP1ALDH1A1HSD17B10 | |
| SCHEMBL4833629 | 0.82 | PGR (0.49) | PGRSOS1NR3C1TDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1357109-B1 | Process for aryl alkyl sulfide | HOFFMANN LA ROCHE (CH) | 2008-07-23 | — | — | EP | disclosed |