Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL4641328

OCC(CO)(CO)CO.OCCOCCO

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.67
MAPK1 P28482 1/20 0.67
MEN1 O00255 3/20 0.62
KMT2A Q03164 3/20 0.62
ALDH1A1 P00352 3/20 0.45
THRB P10828 1/20 0.40
HTT P42858 1/20 0.40
MAPT P10636 1/20 0.40
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triethylene Glycol SCHEMBL8468778 0.97 MEN1 (0.69) TSHRMAPK1MEN1KMT2AALDH1A1
Triethylene Glycol SCHEMBL6254377 0.87 MEN1 (0.55) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL3839562 0.85 TSHR (0.56) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL11670277 0.83 MEN1 (0.58) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL14198257 0.83 MEN1 (0.58) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL2943020 0.83 TSHR (0.53) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL2410410 0.82 TSHR (1.00) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL1462 0.82
SCHEMBL15463146 0.81 TSHR (0.50) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL25885638 0.81 TSHR (0.50) TSHRMAPK1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115521517-B Functional modification of regenerated rubber material and application of regenerated rubber material in safety gloves 浙江康隆达特种防护科技股份有限公司 2023-09-08 CN claimed
CN-117396270-A Aqueous dispersion of microcapsules, and use thereof 高砂香料工业株式会社 2024-01-12 CN disclosed
CN-115521517-B Functional modification of regenerated rubber material and application of regenerated rubber material in safety gloves 浙江康隆达特种防护科技股份有限公司 2023-09-08 CN disclosed
US-20190284152-A1 Maleinated Derivatives ELEVANCE RENEWABLE SCIENCES, INC. (US) 2019-09-19 US disclosed
US-10294210-B2 Maleinated derivatives ELEVANCE RENEWABLE SCIENCES, INC. (US) 2019-05-21 US disclosed
US-20180111912-A1 Maleinated Derivatives ELEVANCE RENEWABLE SCIENCES, INC. (US) 2018-04-26 US disclosed
US-9896424-B2 Methods of making sulfurized derivatives ELEVANCE RENEWABLE SCIENCES, INC. (US) 2018-02-20 US disclosed
US-9738618-B2 Malienated derivatives ELEVANCE RENEWABLE SCIENCES, INC. (US) 2017-08-22 US disclosed
US-20160355492-A1 Methods of Making Sulfurized Derivatives ELEVANCE RENEWABLE SCIENCES, INC. (US) 2016-12-08 US disclosed
CN-103562362-B The monomer of functionalization 艾勒旺斯可再生科学公司 2016-09-14 CN disclosed
EP-0309481-A1 PHOSPHORUS-CONTAINING LUBRICANT AND FUNCTIONAL FLUID COMPOSITIONS. LUBRIZOL CORP (US) 1989-04-05 EP disclosed
EP-0309486-A1 PHOSPHOROUS- AND SULFUR-CONTAINING LUBRICANT AND FUNCTIONAL FLUID COMPOSITIONS The Lubrizol Corporation (US) 1989-04-05 EP disclosed
EP-0291521-A1 SULFUR-CONTAINING COMPOSITIONS, LUBRICANT, FUEL AND FUNCTIONAL FLUID COMPOSITIONS. LUBRIZOL CORP (US) 1988-11-23 EP disclosed
WO-1988003552-A2 SULFUR-CONTAINING COMPOSITIONS, LUBRICANT, FUEL AND FUNCTIONAL FLUID COMPOSITIONS THE LUBRIZOL CORPORATION (US) 1988-05-19 WO disclosed
WO-1987007638-A2 PHOSPHOROUS- AND SULFUR-CONTAINING LUBRICANT AND FUNCTIONAL FLUID COMPOSITIONS THE LUBRIZOL CORPORATION (US) 1987-12-17 WO disclosed
WO-1987007637-A2 PHOSPHORUS-CONTAINING LUBRICANT AND FUNCTIONAL FLUID COMPOSITIONS THE LUBRIZOL CORPORATION (US) 1987-12-17 WO disclosed
EP-0248192-A2 Liquid coating composition STERLING DRUG INC. (US) 1987-12-09 EP disclosed
US-4615739-A MIXTURE OF OIL SOLUBLE RESIN SOLUTION, WATER INSOLUBLE RESIN EMULSION, AND HYDRATED STARCH DISPERSANT FORMBY'S INC. (US) 1986-10-07 US disclosed
EP-0194514-A2 Oil-in-water-in-oil coating composition Formby's Inc. (US) 1986-09-17 EP disclosed
US-4276329-A STABILIZATION BY DEPOSITING RESIN IN CELL WALLS AND CONVERTING RESIN TO WATER INSOLUBLE FORM ENVIROSOL SYSTEMS INTERNATIONAL, LTD. (US) 1981-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180111912-A1 Maleinated Derivatives SMOX, SRM, PADI2 TSHR 4723/4885MAPK1 1841/4885MEN1 59/4885
US-20190284152-A1 Maleinated Derivatives SMOX, SRM, PADI2 TSHR 4723/4885MAPK1 1841/4885MEN1 59/4885
US-20160355492-A1 Methods of Making Sulfurized Derivatives GPX4, CBS, ESD TSHR 4776/4885MAPK1 3239/4885MEN1 3998/4885
US-10294210-B2 Maleinated derivatives SMOX, SRM, PADI2 TSHR 4719/4885MAPK1 1741/4885MEN1 58/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.