Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR1F | P30939 | 2/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5246118 | 0.87 | MCHR1 (0.50) | PTGDR2MAPTTP53RAB9AHTR1A | |
| SCHEMBL4646624 | 0.87 | MAPT (0.42) | PTGDR2MAPTTP53RAB9AHTR1A | |
| SCHEMBL3750082 | 0.85 | MCHR1 (0.51) | MAPTTP53HTR1AHTR1FHTR1B | |
| SCHEMBL4641252 | 0.83 | PTGDR2 (0.39) | PTGDR2MAPTTP53RAB9AHTR1A | |
| SCHEMBL4641350 | 0.81 | MAPT (0.42) | MAPTTP53RAB9ATHRBMCHR1 | |
| SCHEMBL4641368 | 0.81 | PTGDR2 (0.40) | PTGDR2MAPTTP53HTR1FTHRB | |
| SCHEMBL5251678 | 0.81 | MAPT (0.56) | MAPTTP53HTR1AHTR1FHTR1B | |
| SCHEMBL4643098 | 0.81 | MAPT (0.46) | PTGDR2MAPTTP53RAB9AHTR1F | |
| Hydrochloric Acid SCHEMBL5246485 | 0.80 | MAPT (0.55) | MAPTTP53HTR1AHTR1FHTR1B | |
| SCHEMBL4641300 | 0.80 | AGPAT2 (0.42) | MAPTTP53RAB9ATHRBMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828177-B1 | NOVEL MCH RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-08-13 | — | — | EP | claimed |