Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | TP53 | P04637 | 5/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR1F | P30939 | 2/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4641300 | 0.92 | AGPAT2 (0.42) | MAPTTP53THRBKDM4EALDH1A1 | |
| SCHEMBL4641368 | 0.92 | PTGDR2 (0.40) | MAPTTP53PTGDR2THRBMCHR1 | |
| SCHEMBL4643098 | 0.92 | MAPT (0.46) | MAPTTP53PTGDR2KDM4EALDH1A1 | |
| SCHEMBL4643115 | 0.90 | PTGDR2 (0.43) | MAPTTP53PTGDR2THRBKDM4E | |
| SCHEMBL4641252 | 0.88 | PTGDR2 (0.39) | MAPTTP53PTGDR2THRBKDM4E | |
| SCHEMBL5251678 | 0.87 | MAPT (0.56) | MAPTTP53THRBKDM4EALDH1A1 | |
| SCHEMBL4642954 | 0.87 | PTGDR2 (0.39) | MAPTTP53PTGDR2THRBKDM4E | |
| SCHEMBL4641201 | 0.86 | AGPAT2 (0.42) | MAPTPTGDR2THRBKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL5246485 | 0.86 | MAPT (0.55) | MAPTTP53THRBKDM4EALDH1A1 | |
| SCHEMBL4641410 | 0.86 | AGPAT2 (0.42) | MAPTPTGDR2THRBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828177-B1 | NOVEL MCH RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-08-13 | — | — | EP | claimed |