SCHEMBL4643559

SCHEMBL4643559

CCCC[Si](C)(C)OC(=O)CCO

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.39
DGKA P23743 1/20 0.34
ACHE P22303 2/20 0.34
MAPT P10636 1/20 0.34
MAPK1 P28482 1/20 0.34
CES2 O00748 2/20 0.33
CES1 P23141 2/20 0.33
CA12 O43570 1/20 0.33
CA14 Q9ULX7 1/20 0.33
LMNA P02545 2/20 0.32
ALDH1A1 P00352 2/20 0.32
TSHR P16473 1/20 0.32
MGLL Q99685 1/20 0.32
KDM4E B2RXH2 1/20 0.32
DUSP3 P51452 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4644370 0.91 DGKA (0.37) NAAADGKAACHEMAPTMAPK1
SCHEMBL6545806 0.90 TSHR (0.39) DGKACES2CES1CA12CA14
SCHEMBL4643673 0.89 DGKA (0.40) DGKAACHEMAPTMAPK1LMNA
SCHEMBL14735468 0.88 CES1 (0.41) DGKAMAPTMAPK1CES2CES1
SCHEMBL6546145 0.88 TSHR (0.44) NAAADGKAMAPTMAPK1CES2
SCHEMBL2599070 0.88 ALDH1A1 (0.44) DGKACES2CES1CA12CA14
SCHEMBL28423837 0.85 DGKA (0.52) DGKAMAPTMAPK1CES2CES1
SCHEMBL4643789 0.84 MAPT (0.32) NAAADGKAACHEMAPTMAPK1
SCHEMBL6658596 0.83 AKR1B1 (0.43) MAPTALDH1A1TSHRMEN1KMT2A
SCHEMBL4644437 0.83 DGKA (0.33) DGKAMAPTMAPK1CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed