SCHEMBL4643789

SCHEMBL4643789

CCCC[Si](C)(C)OC(=O)CO

nearest known ligand 0.32

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.32
ACHE P22303 2/20 0.32
MAPK1 P28482 1/20 0.32
NAAA Q02083 1/20 0.32
DGKA P23743 1/20 0.32
EPHX1 P07099 3/20 0.31
ALDH1A1 P00352 2/20 0.31
CES2 O00748 2/20 0.31
CES1 P23141 2/20 0.31
CA12 O43570 1/20 0.31
CA14 Q9ULX7 1/20 0.31
LMNA P02545 2/20 0.31
KDM4E B2RXH2 1/20 0.30
DUSP3 P51452 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6545806 0.85 TSHR (0.39) DGKAALDH1A1CES2CES1CA12
SCHEMBL570531 0.85 NAAA (0.42) ACHENAAADGKAEPHX1ALDH1A1
SCHEMBL4643559 0.84 NAAA (0.39) MAPTACHEMAPK1NAAADGKA
SCHEMBL6546145 0.83 TSHR (0.44) MAPTMAPK1NAAADGKAALDH1A1
SCHEMBL14735468 0.83 CES1 (0.41) MAPTMAPK1DGKAALDH1A1CES2
SCHEMBL2599070 0.83 ALDH1A1 (0.44) DGKAALDH1A1CES2CES1CA12
SCHEMBL4644370 0.82 DGKA (0.37) MAPTACHEMAPK1NAAADGKA
SCHEMBL4645281 0.82 FAAH (0.35) ACHEEPHX1ALDH1A1CA12CA14
SCHEMBL4642164 0.82 NAAA (0.31) ACHENAAADGKAEPHX1ALDH1A1
SCHEMBL4643673 0.81 DGKA (0.40) MAPTACHEMAPK1DGKAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed