⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10813588 | 0.86 | KEAP1 (0.34) | — | |
| SCHEMBL17675426 | 0.79 | — | — | |
| SCHEMBL7672273 | 0.78 | — | — | |
| SCHEMBL7275301 | 0.77 | — | — | |
| SCHEMBL11407357 | 0.77 | HRH3 (0.32) | — | |
| SCHEMBL371279 | 0.74 | GNAI3 (0.33) | — | |
| SCHEMBL9321327 | 0.73 | ALOX15 (0.47) | — | |
| SCHEMBL5161248 | 0.73 | — | — | |
| SCHEMBL7121806 | 0.73 | — | — | |
| SCHEMBL3385324 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743353-B2 | Additive combinations for lubricants and functional fluids | LUBRIZOL CORP (US) | 2008-08-06 | — | — | EP | disclosed |
| US-6517811-B2 | Diagnosing a mammal for presence of a tumor by administering compounds such as 125-I-(2-piperidinylaminoethyl)-4-iodobenzamide which have an affinity for cell surface sigma receptors | RESEARCH CORPORATION TECHNOLOGIES, INC. | 2003-02-11 | — | — | US | disclosed |
| EP-0743353-B1 | Additive combinations for lubricants and functional fluids | LUBRIZOL CORP (US) | 2003-01-02 | — | — | EP | disclosed |
| US-6447748-B1 | Benzamide compounds for cancer imaging and therapy | RESEARCH CORPORATION TECHNOLOGIES, INC. | 2002-09-10 | — | — | US | disclosed |
| US-20010006619-A1 | Compounds for cancer imaging and therapy | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2001-07-05 | — | — | US | disclosed |
| US-6015543-A | DIAGNOSIS OF TUMORS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2000-01-18 | — | — | US | disclosed |
| US-5993777-A | Benzamide compounds for cancer imaging and therapy | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1999-11-30 | — | — | US | disclosed |
| US-5911970-A | ANTITUMOR AGENTS AND ANTICARCINOGENIC AGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1999-06-15 | — | — | US | disclosed |
| EP-0821594-A1 | COMPOUNDS FOR CANCER IMAGING AND THERAPY | JOHN, Christy S. (US) | 1998-02-04 | — | — | EP | disclosed |
| US-5681797-A | HYDROGENATED POLYISOPRENE WITH ALKYL PHENOLS OR PHENOLIC ETHERS, MONO- OR DIGLYCERIDES, PHOSPHOROUS COMPOUNDS WITH NITROGEN, OXYGEN AND/OR SULFUR, AROMATIC AMINES, SMALL POLYACRYLIC ESTERS OR POLYOLEFINS AS PERFORMANENCE ADDITIVES | THE LUBRIZOL CORPORATION (US) | 1997-10-28 | — | — | US | disclosed |
| US-5157088-A | Nitrogen-containing esters of carboxy-containing interpolymers | DISHONG DENNIS M (US) | 1992-10-20 | — | — | US | disclosed |
| EP-0203991-B1 | POLYMERIC COMPOSITIONS, OIL COMPOSITIONS CONTAINING SAID POLYMERIC COMPOSITIONS, TRANSMISSION FLUIDS AND HYDRAULIC FLUIDS | The Lubrizol Corporation (US) | 1992-05-27 | — | — | EP | disclosed |
| EP-0354224-A1 | NITROGEN-CONTAINING ESTERS OF CARBOXY-CONTAINING INTERPOLYMERS | The Lubrizol Corporation (US) | 1990-02-14 | — | — | EP | disclosed |
| WO-1989004845-A1 | NITROGEN-CONTAINING ESTERS OF CARBOXY-CONTAINING INTERPOLYMERS | THE LUBRIZOL CORPORATION (US) | 1989-06-01 | — | — | WO | disclosed |
| US-4734446-A | TRANSMISSION FLUIDS, HYDRAULIC FLUIDS | THE LUBRIZOL CORPORATION (US) | 1988-03-29 | — | — | US | disclosed |
| US-4654403-A | ADDITIVES IN TRANSMISSION AND HYDRAULIC FLUIDS | THE LUBRIZOL CORPORATION (US) | 1987-03-31 | — | — | US | disclosed |
| EP-0203991-A1 | POLYMERIC COMPOSITIONS, OIL COMPOSITIONS CONTAINING SAID POLYMERIC COMPOSITIONS, TRANSMISSION FLUIDS AND HYDRAULIC FLUIDS. | LUBRIZOL CORP (US) | 1986-12-10 | — | — | EP | disclosed |
| US-4604221-A | Nitrogen-containing esters and lubricants containing them | THE LUBRIZOL CORPORATION (US) | 1986-08-05 | — | — | US | disclosed |
| US-4594378-A | Blend of oil soluble homopolymer of non-aromatic mono-olefin and nitrogen-containing ester of a carboxy containing interpolymer | THE LUBRIZOL CORPORATION (US) | 1986-06-10 | — | — | US | disclosed |
| WO-1986003221-A1 | POLYMERIC COMPOSITIONS, OIL COMPOSITIONS CONTAINING SAID POLYMERIC COMPOSITIONS, TRANSMISSION FLUIDS AND HYDRAULIC FLUIDS | THE LUBRIZOL CORPORATION (US) | 1986-06-05 | — | — | WO | disclosed |