SCHEMBL464388

SCHEMBL464388

Cc1ccc(S(=O)(=O)OCc2cc(Br)cc(COS(=O)(=O)c3ccc(C)cc3)c2OS(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43
HTT P42858 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
THRB P10828 1/20 0.38
KEAP1 Q14145 1/20 0.38
NFE2L2 Q16236 1/20 0.38
CYP2C19 P33261 1/20 0.37
ESR1 P03372 1/20 0.37
GAA P10253 1/20 0.37
ESR2 Q92731 1/20 0.37
STAT3 P40763 1/20 0.36
P2RY12 Q9H244 1/20 0.36
CYP1A2 P05177 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA9 Q16790 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13024354 0.80 THRB (0.44) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL11626961 0.80 KMT2A (0.53) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL14397286 0.78 P2RY12 (0.37) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL14369561 0.77 MEN1 (0.46) MEN1KMT2AALDH1A1LMNAHTT
SCHEMBL378265 0.77 PTGS2 (0.38) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL8061919 0.76 VDR (0.47) MEN1KMT2AALDH1A1LMNAHTT
SCHEMBL7909564 0.75 CA2 (0.54) MEN1KMT2AALDH1A1MAPTCYP2C19
SCHEMBL19207382 0.75 ALDH1A1 (0.42) MEN1KMT2AALDH1A1MAPTHTT
SCHEMBL17332082 0.74 KMT2A (0.41) MEN1KMT2AALDH1A1MAPTSMN1; SMN2
SCHEMBL17630126 0.74 PSEN1 (0.41) KMT2AALDH1A1CYP2C19CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170194985-A1 METHODS AND COMPUTER PROGRAM PRODUCTS FOR COMPRESSION OF SEQUENCING DATA Life Technologies Corporation 2017-07-06 US disclosed
US-20170145497-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS Life Technologies Corporation 2017-05-25 US disclosed
US-9515676-B2 Methods and computer program products for compression of sequencing data Life Technologies Corporation (US) 2016-12-06 US disclosed
US-9458502-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2016-10-04 US disclosed
US-9404920-B2 Methods and apparatus for detecting molecular interactions using FET arrays Life Technologies Corporation (US) 2016-08-02 US disclosed
US-9194000-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2015-11-24 US disclosed
EP-2307577-B1 METHODS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS LIFE TECHNOLOGIES CORP (US) 2015-06-03 EP disclosed
US-9039888-B2 Methods and apparatus for detecting molecular interactions using FET arrays Life Technologies Corporation (US) 2015-05-26 US disclosed
US-20150126378-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS LIFE TECHNOLOGIES CORP (US) 2015-05-07 US disclosed
US-20140324376-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES Life Technologies Corporation 2014-10-30 US disclosed
US-20120061733-A1 METHODS AND APPARATUS FOR DETECTING MOLECULAR INTERACTIONS USING FET ARRAYS Life Technologies Corporation (US) 2012-03-15 US disclosed
US-20120013392-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES Life Technologies Corporation (US) 2012-01-19 US disclosed
US-20110281741-A1 Method and Apparatus for Rapid Nucleic Acid Sequencing Life Technologies Corporation (US) 2011-11-17 US disclosed
US-20110281737-A1 Method and Apparatus for Rapid Nucleic Acid Sequencing Life Technologies Corporation (US) 2011-11-17 US disclosed
US-20110275522-A1 Method and Apparatus for Rapid Nucleic Acid Sequencing Life Technologies Corporation (US) 2011-11-10 US disclosed
US-20110248320-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES Life Technologies Corporation (US) 2011-10-13 US disclosed
US-20110217697-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS Life Technologies Corporation (CA) 2011-09-08 US disclosed
US-20100301398-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES ION TORRENT SYSTEMS INCORPORATED (US) 2010-12-02 US disclosed
US-20100282617-A1 METHODS AND APPARATUS FOR DETECTING MOLECULAR INTERACTIONS USING FET ARRAYS ION TORRENT SYSTEMS INCORPORATED (US) 2010-11-11 US disclosed
US-20100137143-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES ION TORRENT SYSTEMS INCORPORATED (US) 2010-06-03 US disclosed