SCHEMBL4647641

SCHEMBL4647641

CC(C)(C)[Si](OC(=O)CCl)(c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.36
HIF1A Q16665 2/20 0.36
TRPA1 O75762 1/20 0.36
MAPK1 P28482 1/20 0.36
GSK3B P49841 1/20 0.36
NPC1 O15118 1/20 0.33
POLB P06746 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CYP2C19 P33261 1/20 0.33
JAK2 O60674 1/20 0.33
XDH P47989 1/20 0.33
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4644075 0.87 HIF1A (0.32) ALDH1A1HIF1ATRPA1MAPK1GSK3B
SCHEMBL6546547 0.86 CYP2C19 (0.35) ALDH1A1HIF1APOLBKMT2ACYP2C19
SCHEMBL6072557 0.86 ABL1 (0.35) HIF1ANPC1POLBHTTCYP2C19
SCHEMBL4644895 0.85 TSHR (0.35) ALDH1A1HIF1AMAPK1CYP2C19SMN1; SMN2
SCHEMBL9845210 0.85 ELANE (0.39) ALDH1A1HIF1AKMT2ACYP2C19SMN1; SMN2
SCHEMBL4642010 0.84 ALDH1A1 (0.35) ALDH1A1RAB9AKMT2ALMNASMN1; SMN2
SCHEMBL6072563 0.83 CYP2C19 (0.37) HIF1APOLBHTTCYP2C19MTNR1A
SCHEMBL6545076 0.83 KDM4E (0.36) ALDH1A1HIF1AKMT2ACYP2C19LMNA
SCHEMBL4647513 0.83 CYP2C19 (0.33) ALDH1A1HIF1AHTTKMT2ACYP2C19
SCHEMBL4641886 0.83 SMN1; SMN2 (0.35) ALDH1A1KMT2ALMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed