SCHEMBL4644895

SCHEMBL4644895

CC(C)(C)[Si](OC(=O)CO)(c1ccccc1)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.35
CYP2C19 P33261 1/20 0.34
HIF1A Q16665 1/20 0.34
ALDH1A1 P00352 3/20 0.33
MAPK1 P28482 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MAPT P10636 1/20 0.33
HDAC3 O15379 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC10 Q969S8 1/20 0.33
HDAC11 Q96DB2 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
HDAC9 Q9UKV0 1/20 0.33
HDAC5 Q9UQL6 1/20 0.33
ABL1 P00519 1/20 0.33
ADRB2 P07550 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6546547 0.88 CYP2C19 (0.35) TSHRCYP2C19HIF1AALDH1A1MAPT
SCHEMBL6072557 0.88 ABL1 (0.35) TSHRCYP2C19HIF1AMAPTHDAC3
SCHEMBL4644661 0.87 CYP2C19 (0.33) TSHRCYP2C19HIF1AALDH1A1MAPT
SCHEMBL9845210 0.86 ELANE (0.39) CYP2C19HIF1AALDH1A1L3MBTL1MAPT
SCHEMBL6545076 0.85 KDM4E (0.36) TSHRCYP2C19HIF1AALDH1A1MAPT
SCHEMBL4647641 0.85 ALDH1A1 (0.36) TSHRCYP2C19HIF1AALDH1A1MAPK1
SCHEMBL4647513 0.85 CYP2C19 (0.33) TSHRCYP2C19HIF1AALDH1A1MAPT
SCHEMBL6072563 0.85 CYP2C19 (0.37) TSHRCYP2C19HIF1AMAPTABL1
SCHEMBL4641522 0.84 KDM4E (0.34) ALDH1A1MAPTADRB2ADRB1ADRB3
SCHEMBL6656947 0.83 NR4A2 (0.38) CYP2C19HIF1AALDH1A1MAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed