Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4645863 | 0.87 | LMNA (0.30) | LMNATDP1 | |
| SCHEMBL4643587 | 0.81 | ALDH1A1 (0.34) | LMNATDP1ALDH1A1CES2CES1 | |
| SCHEMBL4643854 | 0.80 | ALDH1A1 (0.37) | LMNATDP1ALDH1A1CES2CES1 | |
| SCHEMBL4647341 | 0.77 | ALDH1A1 (0.34) | LMNATDP1ALDH1A1CES2CES1 | |
| SCHEMBL4644321 | 0.73 | ALDH1A1 (0.38) | LMNAALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL4643335 | 0.71 | ALDH1A1 (0.38) | LMNATDP1ALDH1A1CES2CES1 | |
| SCHEMBL6555621 | 0.70 | LMNA (0.36) | LMNATDP1ALDH1A1CES2CES1 | |
| SCHEMBL4858072 | 0.62 | ACHE (0.47) | LMNATDP1ALDH1A1NPC1MAPT | |
| SCHEMBL4688132 | 0.61 | ALDH1A1 (0.43) | LMNAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL2873305 | 0.60 | ACHE (0.44) | LMNATDP1ALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487928-B1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | JOTUN AS (NO) | 2008-08-13 | — | — | EP | disclosed |