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SCHEMBL4645863

SCHEMBL4645863

[CH2]CCC(C(=O)O[SiH2]c1ccc(C)cc1)(C(=O)O[SiH2]c1ccc(C)cc1)C(=O)O[SiH2]c1ccc(C)cc1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.30
▸ TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4645470 0.87 LMNA (0.32) LMNATDP1
SCHEMBL4643587 0.78 ALDH1A1 (0.34) LMNATDP1
SCHEMBL4643854 0.78 ALDH1A1 (0.37) LMNATDP1
SCHEMBL4647341 0.75 ALDH1A1 (0.34) LMNATDP1
SCHEMBL4644321 0.71 ALDH1A1 (0.38) LMNA
SCHEMBL4643335 0.69 ALDH1A1 (0.38) LMNATDP1
SCHEMBL6555621 0.68 LMNA (0.36) LMNATDP1
SCHEMBL4858072 0.60 ACHE (0.47) LMNATDP1
SCHEMBL1040708 0.59 KMT2A (0.64) LMNA
SCHEMBL2873305 0.58 ACHE (0.44) LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 — — EP disclosed