SCHEMBL2873305

SCHEMBL2873305

CO[SiH2]c1ccc(C)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 7/20 0.44
TDP1 Q9NUW8 3/20 0.44
TSHR P16473 4/20 0.38
CA2 P00918 2/20 0.36
LPL P06858 1/20 0.36
LIPG Q9Y5X9 1/20 0.36
ORAI1 Q96D31 1/20 0.36
ORAI2 Q96SN7 1/20 0.36
ORAI3 Q9BRQ5 1/20 0.36
TRPV6 Q9H1D0 1/20 0.36
ALDH1A1 P00352 3/20 0.35
CA1 P00915 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
RELA Q04206 1/20 0.34
CYP3A4 P08684 1/20 0.32
TEAD4 Q15561 1/20 0.32
AGXT P21549 1/20 0.32
LMNA P02545 1/20 0.32
ALOX12 P18054 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4858072 0.80 ACHE (0.47) ACHETDP1TSHRCA2LPL
SCHEMBL12587846 0.80 ESR2 (0.33)
SCHEMBL8579309 0.76 TDP1 (0.46) ACHETDP1TSHRALDH1A1CYP3A4
SCHEMBL50084 0.74
SCHEMBL8017963 0.74 MAPT (0.34) TDP1MAPT
SCHEMBL3481748 0.72 ALDH1A1 (0.36) ACHETDP1TSHRALDH1A1CYP3A4
SCHEMBL3481787 0.72 ACHE (0.38) ACHETDP1CA2LPLLIPG
SCHEMBL17835350 0.72 ACHE (0.38) ACHETDP1CA2LPLLIPG
SCHEMBL3482550 0.72 LPL (0.43) TDP1TSHRCA2LPLLIPG
SCHEMBL16301269 0.72 ACHE (0.61) ACHETDP1TSHRCA2LPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104789111-B Oligoaniline compound 日产化学工业株式会社 2018-05-01 CN disclosed
CN-104821375-B Oligoaniline compound 日产化学工业株式会社 2018-03-02 CN disclosed
CN-104487516-B Polysiloxane composition, electronic device and optics 东丽株式会社 2017-10-24 CN disclosed
CN-101679206-B oligoaniline compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-05-11 CN disclosed
EP-2143708-B1 OLIGOANILINE COMPOUND NISSAN CHEMICAL IND LTD (JP) 2016-04-06 EP disclosed
US-9268451-B2 Transfer film, manufacturing method of capacitive input device, capacitive input device, and image display device including the same FUJIFILM CORPORATION (JP) 2016-02-23 US disclosed
CN-104821375-A OLIGOANILINE COMPOUND NISSAN CHEMICAL IND LTD 2015-08-05 CN disclosed
CN-104789111-A Oligoaniline compound NISSAN CHEMICAL IND LTD 2015-07-22 CN disclosed
EP-2128897-B1 SILICON DIELECTRIC TREATING AGENT FOR USE AFTER ETCHING, PROCESS FOR PRODUCING SEMICONDUCTOR DEVICE, AND SEMICONDUCTOR DEVICE FUJITSU LTD (JP) 2015-05-06 EP disclosed
US-20150092123-A1 TRANSFER FILM, MANUFACTURING METHOD OF CAPACITIVE INPUT DEVICE, CAPACITIVE INPUT DEVICE, AND IMAGE DISPLAY DEVICE INCLUDING THE SAME FUJIFILM CORPORATION (JP) 2015-04-02 US disclosed
US-8716209-B2 Agent for post-etch treatment of silicon dielectric film, method of manufacturing semiconductor device, and semiconductor device FUJITSU LIMITED (JP) 2014-05-06 US disclosed
US-8298444-B2 Oligoaniline compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-10-30 US disclosed
US-20100230639-A1 OLIGOANILINE COMPOUND NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-09-16 US disclosed
CN-101679206-A Oligoaniline compound NISSAN CHEMICAL IND LTD 2010-03-24 CN disclosed
US-20100007031-A1 AGENT FOR POST-ETCH TREATMENT OF SILICON DIELECTRIC FILM, METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE, AND SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2010-01-14 US disclosed
EP-2143708-A1 OLIGOANILINE COMPOUND Nissan Chemical Industries, Ltd. (JP) 2010-01-13 EP disclosed
EP-2128897-A1 SILICON DIELECTRIC TREATING AGENT FOR USE AFTER ETCHING, PROCESS FOR PRODUCING SEMICONDUCTOR DEVICE, AND SEMICONDUCTOR DEVICE Fujitsu Limited (JP) 2009-12-02 EP disclosed
CN-1837221-A Production processes for triorganomonochlorosilanes HOKKO CHEM IND CO (JP) 2006-09-27 CN disclosed
CN-1612886-A Method for producing triorgano-monoalkoxysilanes and method for producing triorgano-monochlorosilanes HOKKO CHEM IND CO (JP) 2005-05-04 CN disclosed
EP-0427567-A2 Parabolic antenna reflector and process for preparing same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-05-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100230639-A1 OLIGOANILINE COMPOUND OPRD1, NSD1, OCIAD1 ACHE 2128/4885TDP1 2498/4885TSHR 2115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.