Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.30 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7914615 | 0.82 | LMNA (0.41) | KDM4ELMNAALDH1A1MAPTMEN1 | |
| SCHEMBL6165725 | 0.82 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL7951297 | 0.81 | RXRA (0.37) | ALDH1A1MEN1KMT2ACNR1CNR2 | |
| SCHEMBL15067592 | 0.77 | ALDH1A1 (0.36) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL195576 | 0.76 | LMNA (0.36) | KDM4ELMNAALDH1A1MAPTMEN1 | |
| SCHEMBL60651 | 0.75 | ALDH1A1 (0.40) | ALDH1A1TSHRSMN1; SMN2POLB | |
| SCHEMBL4648041 | 0.75 | ALDH1A1 (0.32) | ALDH1A1MEN1KMT2A | |
| SCHEMBL4648856 | 0.72 | RXRA (0.41) | ALDH1A1MEN1KMT2ACNR1CNR2 | |
| SCHEMBL4457527 | 0.70 | KDM4E (0.33) | KDM4ELMNAALDH1A1MAPTTSHR | |
| SCHEMBL3823195 | 0.67 | ALDH1A1 (0.34) | ALDH1A1CNR1CNR2TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1577314-B1 | Catalyst based on a transition metal complex for polymerization of olefins, and process for polymerization of olefins using the catalyst | TOSOH CORP (JP) | 2008-08-27 | — | — | EP | disclosed |
| US-7153916-B2 | Transition metal compound, catalyst for polymerization of olefin, and process for polymerization of ofelin using the catalyst | TOSOH CORPORATION (JP) | 2006-12-26 | — | — | US | disclosed |
| EP-1577314-A1 | Catalyst based on a transition metal complex for polymerization of olefin, and process for polymerization of olefin using the catalyst | Tosoh Corporation (JP) | 2005-09-21 | — | — | EP | disclosed |
| EP-1241175-B1 | Transition metal compound, catalyst for polymerization of olefin, and process for polymerization of olefin using the catalyst | TOSOH CORP (JP) | 2005-08-31 | — | — | EP | disclosed |
| US-20030018145-A1 | Transition metal compound, catalyst for polymerization of olefin, and process for polymerization of olefin using the catalyst | TOSOH CORPORATION (JP) | 2003-01-23 | — | — | US | disclosed |
| EP-1241175-A2 | Transition metal compound, catalyst for polymerization of olefin, and process for polymerization of olefin using the catalyst | Tosoh Corporation (JP) | 2002-09-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018145-A1 | Transition metal compound, catalyst for polymerization of olefin, and process for polymerization of olefin using the catalyst | PORCN, OSTC, PPOX | KDM4E 3436/4885LMNA 4366/4885ALDH1A1 2770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.