Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Edetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE known ✓ | P12821 | 1/20 | 0.93 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.88 |
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.88 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.88 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.88 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.88 |
| ▸ | DRD3 known ✓ | P35462 | 1/20 | 0.88 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.88 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.93 |
| ▸ | EYA2 | O00167 | 1/20 | 0.93 |
| ▸ | APP | P05067 | 1/20 | 0.93 |
| ▸ | BLM | P54132 | 2/20 | 0.88 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.88 |
| ▸ | TSHR | P16473 | 2/20 | 0.88 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.88 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.88 |
| ▸ | LMNA | P02545 | 1/20 | 0.88 |
| ▸ | DRD1 | P21728 | 1/20 | 0.88 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.88 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Edetic Acid SCHEMBL731870 | 1.00 | TDP1 (0.93) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL11181102 | 1.00 | TDP1 (0.93) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL7794247 | 1.00 | TDP1 (0.93) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL1933603 | 1.00 | TDP1 (0.93) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL9640564 | 1.00 | TDP1 (0.93) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL23455628 | 0.97 | TDP1 (0.88) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL21332394 | 0.97 | TDP1 (0.88) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL291274 | 0.97 | TDP1 (0.88) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL21436997 | 0.97 | TDP1 (0.88) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL20743376 | 0.97 | TDP1 (0.88) | TDP1EYA2APPACEBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 846 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12409155-B1 | Ready to use LET formulations | QuVa Pharma Inc. (US) | 2025-09-09 | — | — | US | claimed |
| WO-2024243119-A2 | PRODUCTS AND METHODS FOR PRESERVING AND DETECTING BIOMOLECULES IN HUMAN SALIVA SAMPLES | SPECTRUM SOLUTIONS L.L.C. (US) | 2024-11-28 | — | — | WO | claimed |
| CN-118140812-A | Method for rapidly breeding monocot scindapsus aureus | 李艺 | 2024-06-07 | — | — | CN | claimed |
| CN-117030646-B | Multi-channel pipette field measurement device and method based on photometry | 中国计量科学研究院 | 2024-01-26 | — | — | CN | claimed |
| CN-117030645-B | Optical system and detection method for single-channel pipettor precision on-site detection | 中国计量科学研究院 | 2024-01-26 | — | — | CN | claimed |
| CN-117030645-A | Optical system and detection method for single-channel pipettor precision on-site detection | 中国计量科学研究院 | 2023-11-10 | — | — | CN | claimed |
| CN-117030646-A | Multi-channel pipette field measurement device and method based on photometry | 中国计量科学研究院 | 2023-11-10 | — | — | CN | claimed |
| US-20230284611-A1 | AQUEOUS SOLUTION TO PRESERVE NUCLEIC ACIDS | BIOFARMA S R L (IT) | 2023-09-14 | — | — | US | claimed |
| EP-4188082-A1 | AQUEOUS SOLUTION TO PRESERVE NUCLEIC ACIDS | Biofarma S.r.l. (IT) | 2023-06-07 | — | — | EP | claimed |
| CN-114411414-A | Palladium-free chemical copper plating method for surface of flexible nanofiber membrane | 武汉纺织大学 | 2022-04-29 | — | — | CN | claimed |
| US-20150056625-A1 | REAGENT FOR CLARIFYING EMULSIONS AND METHOD OF CLARIFICATION | BENTLEY INSTRUMENTS S.A.R.L. (FR) | 2015-02-26 | — | — | US | claimed |
| CN-104272081-A | Reagent for clarifying emulsion and method of clarifying | BENTLEY INSTR S A R L | 2015-01-07 | — | — | CN | claimed |
| WO-2013167150-A1 | REAGENT FOR CLARIFYING EMULSIONS AND METHOD OF CLARIFICATION | BENTLEY INSTRUMENTS S.A.R.L. (FR) | 2013-11-14 | — | — | WO | claimed |
| US-6190443-B1 | Polishing composition | FUJIMI INCORPORATED (JP) | 2001-02-20 | — | — | US | claimed |
| US-5961939-A | Process for recovery of silver from hardening photoprocessing solutions | EASTMAN KODAK COMPANY (US) | 1999-10-05 | — | — | US | claimed |
| EP-0864923-A1 | Process for the recovery of silver from hardening photoprocessing solutions | EASTMAN KODAK COMPANY (US) | 1998-09-16 | — | — | EP | claimed |
| WO-1993025521-A1 | ARYL ALIPHATIC ACIDS | BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) | 1993-12-23 | — | — | WO | claimed |
| US-5238832-A | Lipoxygenase inhibitors | BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) | 1993-08-24 | — | — | US | claimed |
| US-4883792-A | ANTIFUNGAL CREAM CONTAINING TIPREDANE | E.R. SQUIBB & SONS, INC., A DE CORP. | 1989-11-28 | — | — | US | claimed |
| US-3959491-A | SORBIC ACID, 1-(3-CHLOROALLYL)-3,5,7-TRIAZA-1-AZONIAADAMANTANE CHLORIDE | STIEFEL LABORATORIES, INC. (US) | 1976-05-25 | — | — | US | claimed |