Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Edetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE known ✓ | P12821 | 1/20 | 0.93 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.88 |
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.88 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.88 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.88 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.88 |
| ▸ | DRD3 known ✓ | P35462 | 1/20 | 0.88 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.88 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.93 |
| ▸ | EYA2 | O00167 | 1/20 | 0.93 |
| ▸ | APP | P05067 | 1/20 | 0.93 |
| ▸ | BLM | P54132 | 2/20 | 0.88 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.88 |
| ▸ | TSHR | P16473 | 2/20 | 0.88 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.88 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.88 |
| ▸ | LMNA | P02545 | 1/20 | 0.88 |
| ▸ | DRD1 | P21728 | 1/20 | 0.88 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.88 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Edetic Acid SCHEMBL11181102 | 1.00 | TDP1 (0.93) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL464945 | 1.00 | TDP1 (0.93) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL7794247 | 1.00 | TDP1 (0.93) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL1933603 | 1.00 | TDP1 (0.93) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL9640564 | 1.00 | TDP1 (0.93) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL23455628 | 0.97 | TDP1 (0.88) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL21332394 | 0.97 | TDP1 (0.88) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL291274 | 0.97 | TDP1 (0.88) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL21436997 | 0.97 | TDP1 (0.88) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL20743376 | 0.97 | TDP1 (0.88) | TDP1EYA2APPACEBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4772415-A | Heavy duty degreaser composition and method of use | ADONE DONALD J (US) | 1988-09-20 | — | — | US | claimed |
| JP-8259498-A | — | — | None | — | — | JP | disclosed |
| WO-2026105829-A1 | POLYPHENYLENE ETHER SOLUTION, POROUS MEMBRANE, METHOD FOR PRODUCING POROUS MEMBRANE, ALKALI ELECTROLYSIS DIAPHRAGM, PHARMACEUTICAL PROCESS FILTER, AND WATER TREATMENT MEMBRANE | 旭化成株式会社 | 2026-05-21 | — | — | WO | disclosed |
| CN-108350396-B | Cleaning and disinfecting compositions | 美国消毒公司 | 2021-08-20 | — | — | CN | disclosed |
| EP-3731958-A1 | SURFACTANT COMPOSITIONS AND USES AS INVERTERS | Ecolab USA, Inc. (US) | 2020-11-04 | — | — | EP | disclosed |
| EP-3497262-A1 | PRETREATMENT COMPOSITION | PPG Industries Ohio, Inc. (US) | 2019-06-19 | — | — | EP | disclosed |
| US-10040957-B2 | Ink jettable, UV-curable compositions | EASTMAN KODAK COMPANY (US) | 2018-08-07 | — | — | US | disclosed |
| CN-108350396-A | Cleaning and sanitizing composition | 美国消毒公司 | 2018-07-31 | — | — | CN | disclosed |
| US-9902168-B2 | UV-curing methods for forming ink jet images | EASTMAN KODAK COMPANY (US) | 2018-02-27 | — | — | US | disclosed |
| CN-107201512-A | Copper plating bath and copper electroplating method | 上村工业株式会社 | 2017-09-26 | — | — | CN | disclosed |
| US-6432439-B1 | COMPRISING FLUOROMETHOLONE OR CLOBETASONE BUTYRATE, OILS, WATER, PHOSPHATIDES AND CELLULOSE; STABLE ANTIINFLAMMATORY AGENTS; SIDE EFFECT REDUCTION | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 2002-08-13 | — | — | US | disclosed |
| US-6156716-A | Heavy duty degreaser cleaning compositions and methods of using the same | KAY CHEMICAL INCORPORATED (US) | 2000-12-05 | — | — | US | disclosed |
| WO-2000068351-A1 | HEAVY DUTY DEGREASER CLEANING COMPOSITIONS AND METHODS OF USING THE SAME | KAY CHEMICAL COMPANY (US) | 2000-11-16 | — | — | WO | disclosed |
| JP-H08259498-A | PURIFICATION OF ESTER | MATSUMOTO YUSHI SEIYAKU CO LTD | 1996-10-08 | — | — | JP | disclosed |
| EP-0503852-A1 | Soap compounded with vitamin B1-containing garlic extract | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-09-16 | — | — | EP | disclosed |
| EP-0456810-A4 | HEAT AND CURE STABLE, FORMULATED CHLORINATED OLEFIN POLYMER | — | 1992-05-20 | — | — | EP | disclosed |
| EP-0456810-A1 | HEAT AND CURE STABLE, FORMULATED CHLORINATED OLEFIN POLYMER | THE DOW CHEMICAL COMPANY (US) | 1991-11-21 | — | — | EP | disclosed |
| WO-1991008255-A1 | HEAT AND CURE STABLE, FORMULATED CHLORINATED OLEFIN POLYMER | THE DOW CHEMICAL COMPANY (US) | 1991-06-13 | — | — | WO | disclosed |
| US-4772415-A | Heavy duty degreaser composition and method of use | ADONE DONALD J (US) | 1988-09-20 | — | — | US | disclosed |
| US-4048426-A | DIISOPRENYL ETHER IN BUTADIENE-STYRENE EMULSION | PHILLIPS PETROLEUM COMPANY (US) | 1977-09-13 | — | — | US | disclosed |