Acrylic Acid

Acrylic Acid

SCHEMBL4649571

C=C(C(=O)O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.C=CC(=O)O

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.48
LMNA P02545 1/20 0.39
ALOX15 P16050 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7083019 0.90 THRB (0.58) THRBLMNACA1CA2MMP1
SCHEMBL10933132 0.90 THRB (0.58) THRBLMNACA1CA2MMP1
SCHEMBL466484 0.90 THRB (0.58) THRBLMNACA1CA2MMP1
SCHEMBL1907684 0.90 THRB (0.58) THRBLMNACA1CA2MMP1
SCHEMBL9163052 0.90 THRB (0.58) THRBLMNACA1CA2MMP1
SCHEMBL23522592 0.90 THRB (0.58) THRBLMNACA1CA2MMP1
SCHEMBL8457919 0.90 THRB (0.58) THRBLMNACA1CA2MMP1
SCHEMBL12475297 0.90 THRB (0.58) THRBLMNACA1CA2MMP1
SCHEMBL1635206 0.88 THRB (0.54) THRBCA1CA2MMP1MMP2
Perflexane SCHEMBL30667525 0.83 LMNA (0.56) THRBLMNAALOX15HSD17B10CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11045833-B2 Task specific ionic liquid-impregnated polymeric surface coatings for antibacterial, antifouling, and metal scavenging activity MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-06-29 US claimed
US-20180009001-A1 METHODS FOR THE VAPOR PHASE DEPOSITION OF POLYMER THIN FILMS MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2018-01-11 US claimed
US-20160333187-A1 SYSTEMS AND METHODS FOR CONTROLLING THE DEGRADATION OF DEGRADABLE MATERIALS DropWise Technologies Corp. 2016-11-17 US claimed
WO-2016183574-A1 SYSTEMS AND METHODS FOR CONTROLLING THE DEGRADATION OF DEGRADABLE MATERIALS BAUER UWE (US) 2016-11-17 WO claimed
US-20160159038-A1 GRAFTED POLYMER SURFACES FOR DROPWISE CONDENSATION, AND ASSOCIATED METHODS OF USE AND MANUFACTURE MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2016-06-09 US claimed
US-20140314982-A1 GRAFTED POLYMER SURFACES FOR DROPWISE CONDENSATION, AND ASSOCIATED METHODS OF USE AND MANUFACTURE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2014-10-23 US claimed
WO-2022146808-A3 OPTICALLY CLEAR, STRETCHABLE, CROSSLINKED THIN FILM POLYMERIC BARRIER LAYERS PROTECTING OPTICAL DEVICES UNIVERSITY OF ROCHESTER (US) 2022-08-04 WO disclosed
WO-2022146808-A2 OPTICALLY CLEAR, STRETCHABLE, CROSSLINKED THIN FILM POLYMERIC BARRIER LAYERS PROTECTING OPTICAL DEVICES UNIVERSITY OF ROCHESTER (US) 2022-07-07 WO disclosed
US-11045833-B2 Task specific ionic liquid-impregnated polymeric surface coatings for antibacterial, antifouling, and metal scavenging activity MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-06-29 US disclosed
US-10766004-B2 Composite membranes and methods of use 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-09-08 US disclosed
US-10755942-B2 Method of forming topcoat for patterning MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2020-08-25 US disclosed
US-20200164319-A1 COMPOSITE MEMBRANES WITH IMPROVED PERFORMANCE AND/OR DURABILITY AND METHODS OF USE 3M INNOVATIVE PROPERTIES COMPANY 2020-05-28 US disclosed
US-20200056054-A1 MULTI-SCALE BLOCK COPOLYMER COATING THAT INDUCES HYDROPHOBIC PROPERTIES MASSACHUSETTS INST TECHNOLOGY (US) 2020-02-20 US disclosed
EP-2956248-A1 GRAFTED POLYMER SURFACES FOR DROPWISE CONDENSATION, AND ASSOCIATED METHODS OF USE AND MANUFACTURE Massachusetts Institute of Technology (US) 2015-12-23 EP disclosed
US-20140314982-A1 GRAFTED POLYMER SURFACES FOR DROPWISE CONDENSATION, AND ASSOCIATED METHODS OF USE AND MANUFACTURE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2014-10-23 US disclosed
WO-2014127304-A1 GRAFTED POLYMER SURFACES FOR DROPWISE CONDENSATION, AND ASSOCIATED METHODS OF USE AND MANUFACTURE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2014-08-21 WO disclosed
EP-1673566-A4 COMPOSITE POLYMER MICROFLUIDIC CONTROL DEVICE EKSIGENT TECHNOLOGIES LLC (US) 2008-08-27 EP disclosed
US-20070272309-A1 Composite Polymer Microfludic Control Device EKSIGENT TECHNOLOGIES, LLC 2007-11-29 US disclosed
EP-1673566-A2 COMPOSITE POLYMER MICROFLUIDIC CONTROL DEVICE Eksigent Technologies, LLC (US) 2006-06-28 EP disclosed
WO-2005028108-A2 COMPOSITE POLYMER MICROFLUIDIC CONTROL DEVICE EKSIGENT TECHNOLOGIES, LLC (US) 2005-03-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11045833-B2 Task specific ionic liquid-impregnated polymeric surface coatings for antibacterial, antifouling, and metal scavenging activity LPO, SOD1, ICMT THRB 3669/4885LMNA 3300/4885ALOX15 49/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.